University Of California, Davis

This study is testing if injecting a special saltwater solution (tumescence) into the thigh before taking a skin graft improves how well the graft heals on a patient's arm or leg after head and neck cancer surgery. Researchers are comparing this technique to the current standard …

This study tests whether brief counseling sessions (5-10 minutes) given by trauma nurses can help injured patients reduce harmful drinking. Researchers enrolled 830 adults hospitalized for injuries who tested positive for alcohol. Participants received either standard care or a s…

This study is testing whether a patient's own muscle cells can safely improve swallowing problems caused by head and neck cancer treatments like surgery or radiation. Researchers take a small muscle sample, grow the cells in a lab, and inject them back into the tongue. The goal i…

This study is comparing newer, less invasive endoscopic procedures to traditional surgery for treating various gastrointestinal conditions. It will involve 500 adults with conditions like achalasia, severe reflux, or issues after weight-loss surgery. The goal is to see if these s…

This early-stage study is checking if it's safe and possible to treat vision loss by injecting a patient's own bone marrow stem cells directly into the eye. It involves 15 adults who have lost vision from conditions like macular degeneration or diabetic retinopathy. The main goal…

This study aims to find out which of two common treatments works better for actinic keratosis, also known as sun spots. Adults with at least 10 sun spots will have one area treated with a freezing spray (cryotherapy) and another with a prescription cream (5-FU). Researchers will …

This small pilot study is testing whether counseling patients with heart failure to follow the DASH diet helps improve their eating habits, symptoms, and key health markers like blood pressure. Researchers are working with 26 stable heart failure patients in an outpatient clinic …

This study is testing whether a 6-month program teaching memory strategies and healthy lifestyle habits can help older adults who are worried about their memory. Participants are randomly placed into one of two groups: one receives general coaching, while the other gets specific …

This study is testing a new type of PET/CT scanner called uEXPLORER to see if it can produce images as good as standard scanners, but in less time. It involves 180 adults with lung cancer, lymphoma, or melanoma who are already scheduled for a standard PET/CT scan. The main goal i…

This study is testing whether a non-invasive finger monitor can predict a dangerous drop in blood pressure (hypotension) as accurately as the current standard method, which requires inserting a needle into an artery. It involves 50 adults who are already scheduled for surgery wit…

This study is testing a new type of PET scan to see if it can accurately measure fat, inflammation, and scarring in the liver. It aims to provide a clearer picture of fatty liver disease without needing a painful biopsy. The study involves 120 adults who are already scheduled for…

This study tests a digital outreach program designed to help women who had diabetes during pregnancy (gestational diabetes) get recommended follow-up screening and join lifestyle programs after giving birth. The goal is to prevent these women from developing type 2 diabetes later…

This study examines whether California's Armed and Prohibited Persons System (APPS) reduces future violence. The system identifies people who legally bought guns but later became prohibited from owning them (due to criminal convictions, mental health issues, or restraining orders…

This small pilot study is testing whether teaching parents to give their newborn babies a gentle abdominal massage can help prevent jaundice. Jaundice is common in newborns and is caused by a buildup of bilirubin. The idea is that massage might help babies pass stool more quickly…

This study is testing whether a specific type of nerve block, given before thyroid surgery, can help reduce pain, nausea, and the need for opioid painkillers afterward. It involves 74 adults having thyroid surgery, who are randomly assigned to receive either the real nerve block …

This study is testing if a specific step during wound closure makes scars look better. Doctors will compare two sides of the same surgical wound on 50 adults: one side will get a standard closure, and the other will get an extra step to loosen the skin at the ends. The goal is to…

This study compares two standard ways to manage pain after surgery to repair a torn ACL knee ligament. Researchers are testing if a numbing injection in the thigh (a nerve block) works as well as taking pain pills by mouth. They will measure participants' pain levels, medication …

This small pilot study is testing whether a daily mushroom extract supplement (AHCC) can improve quality of life for women with ovarian, fallopian tube, or peritoneal cancer who are undergoing standard chemotherapy. Twenty participants will be randomly assigned to take either the…

This study is testing whether very short (5-15 second) mindfulness practices throughout the day can help improve well-being for people struggling with long COVID symptoms. Researchers are enrolling 400 participants who had COVID-19 over 3 months ago and still experience symptoms …

This study is testing whether providing a diabetes coach for six months helps improve the quality of life and reduce stress for families of children who have just been diagnosed with type 1 diabetes. It will compare 60 families who receive the coaching support to families who rec…

This small pilot study is testing whether a telehealth program can help caregivers support infants who show early signs of attention and self-regulation difficulties. The program teaches caregivers strategies to use during daily activities at home. Researchers will see if the pro…

This study is testing whether using sunscreen on a healing surgical scar makes it look better. For each patient, doctors will put zinc sunscreen on one half of the scar and leave the other half untreated. After three months, they will compare both sides to see if the sunscreen he…

This study is testing a new way to teach health by having students create and perform a short play about diet and exercise guidelines. Researchers want to see if this 'health education theater' helps students learn the guidelines, follow them better, and feel better about themsel…

This study aims to see if adding walnuts to the diet changes markers of heart health and the bacteria living in the gut. It involves 30 overweight adults with high LDL ('bad') cholesterol, who will follow specific diets with and without walnuts for several weeks. Researchers will…

This study aims to understand if Kangaroo Care—holding a baby skin-to-skin—affects the amount and nutritional quality of breast milk for parents with infants in the Neonatal Intensive Care Unit (NICU). Researchers are observing 25 parent-infant pairs to measure changes in milk ca…

This study aims to see if a simple, painless eye scan can detect the earliest biological signs of Alzheimer's disease before memory problems begin. Researchers will compare retinal images from people with early chemical markers of Alzheimer's to those without any markers. The goa…

This study aims to understand if bariatric (weight loss) surgery can help improve memory and thinking skills in people with obesity. Researchers will enroll 9,500 participants who have obesity and either have or are at risk for cognitive issues. The study will compare memory test…

This study aims to understand the underlying biology of acne by comparing people with and without the condition. Researchers will analyze the natural oils on the skin, the bacteria on the skin and in the gut, and fats in the blood. They will look at how these factors change in pe…

This study is testing a new training program called TEAMS to help therapists and teachers get better at using proven therapies for children with autism. It involves training leaders and using motivational techniques to help providers stick with the training and use the therapies …

This study is testing whether telehealth tools can help families who have concerns about autism in their infants. Researchers are comparing two online approaches: a remote developmental assessment and a set of parent training videos about communication strategies. They're measuri…

This study aims to create a network of clinics across California to collect and share data on young people experiencing their first episode of psychosis. The goal is to help doctors use this data to make better treatment decisions and to develop a new tool to measure how long peo…

This study aims to understand how the sugars and fats in breast milk differ between mothers, and how a mother's diet, health, and gut bacteria affect her milk. Researchers are observing mothers, including some with diabetes, to see how these milk components influence the developm…

This study aims to understand how certain stomach conditions progress toward cancer. Researchers will follow 1000 UC Davis patients who have these pre-cancerous stomach conditions. They will collect health information and samples over time to identify early warning signs and fact…

This study is testing whether giving a specific probiotic to healthy, breastfed newborns for their first 21 days changes the bacteria in their gut. Researchers will compare babies who get the probiotic to those who don't, checking their stool samples and tracking their general he…

This study aims to understand if a single dose of black rice extract can increase levels of a protein called BDNF in the blood. BDNF is important for brain health, mood, and memory. Researchers will give the extract or a placebo to 12 healthy volunteers and measure BDNF levels in…

This study aims to understand if brain inflammation after a serious head injury increases the risk of developing epilepsy. Researchers will use special PET brain scans on 30 adults at two weeks and two months after their injury to measure this inflammation. The goal is to gather …

This study aims to see if a standard extended-release ADHD medication (methylphenidate) can improve specific thinking skills like attention and memory in children and teens who have both an intellectual disability and ADHD. Researchers will measure changes using a set of computer…

This study aims to understand how popular weight-loss medications (like semaglutide and tirzepatide) affect people's food cravings and the overall quality of their diet. About 150 adults with overweight or obesity will track their eating and cravings over 24 weeks using questionn…

This study aims to understand how eating cheese compared to a non-dairy cheese substitute affects inflammation in the hours after a meal. It involves 20 adults who have risk factors for metabolic syndrome or obesity. Participants eat one type of cheese on separate test days, and …

This study aims to improve how doctors use a special total-body PET scanner to see cancer more clearly. Researchers will test three different FDA-approved imaging agents in people with prostate cancer, breast cancer, or neuroendocrine tumors. The goal is to collect better data on…

This study aims to understand how specific components in dairy fat might influence inflammation in the body after eating a high-fat meal. It involves 38 adults with obesity or metabolic syndrome who will drink different test shakes on separate days. Researchers will measure marke…

This study is testing whether showing educational ads on social media can increase awareness about organ donation and get more people to register as donors. It involves about 2 million California residents who use Facebook. Researchers are measuring if people who see the ads clic…

This study is observing how a baby's gut bacteria change when they first eat solid foods, and how those changes might relate to their development. Researchers are comparing two common first foods—sweet potato and pear—to see how their different carbohydrate types affect the growt…

This study aims to understand if eating different types of olive oil changes markers linked to heart disease risk, like cholesterol levels and inflammation. It involves 44 healthy adults aged 20-45. Participants eat two olive oils (one high-polyphenol, one low-polyphenol) for two…

This study aims to find out if common fingertip oxygen monitors (pulse oximeters) are less accurate for newborns with darker skin, potentially overestimating their oxygen levels. Researchers are observing 163 newborns in intensive care to compare the monitor readings with direct …

This study aims to find out if eating chicken raised using organic farming methods is better for your body than eating conventionally raised chicken. Researchers will measure nutrient levels in the blood and the body's muscle-building response in healthy young adults after they e…

This study aims to find new, measurable signs of myofascial pain using a special full-body PET/CT scanner. Researchers will scan 53 adults with chronic low back pain to see if they can detect changes in muscle tissue related to metabolism and blood flow. The goal is to develop be…