University Of California, Davis

This early-phase trial tested a combination of two drugs, ibrutinib and lenalidomide, in people with myelodysplastic syndrome (MDS) who could not take or chose not to take standard treatments. The main goal was to find the safest dose and identify side effects. Only 4 people took…

This study tested a combination of two drugs, ibrutinib and blinatumomab, in 19 adults with B-cell acute lymphoblastic leukemia that had returned or stopped responding to treatment. The goal was to see how well the drugs worked together to stop cancer growth. The study is complet…

This early-stage trial tested a combination of two drugs—enzalutamide (a standard hormone therapy) and niclosamide (a drug used for worm infections)—in 6 men with advanced prostate cancer that no longer responds to hormone therapy. The goal was to find the safest dose and identif…

This study explored whether qigong, a gentle mind-body practice, could improve health-related quality of life for people with long COVID. Forty adults with lingering symptoms for over 12 weeks participated in the pilot study. Researchers measured changes in physical and mental he…

This study tested whether the Embrace device, applied after skin surgery, improves scar appearance. Twelve adults had half their wound treated with the device and the other half without. Researchers compared scar quality and width between the two sides.

This study tested whether using a gentle suction in the throat could reduce the amount of food or liquid entering the airway during a swallowing exam. It involved one person with severe swallowing problems who relied on a feeding tube and had not improved with other treatments. T…

This study tested a new, FDA-cleared total-body PET/CT scanner on 20 healthy adults from racial/ethnic minority groups. The goal was to collect baseline data on how the body absorbs a tracer, helping future research better understand health differences. Participants had a full-bo…

This study looked at 43 adults having heart surgery to see if a simple artery line could measure heart contraction strength as well as a detailed ultrasound. The goal was to find a faster, easier way to check heart function during operations. The results help doctors understand h…

This study tested whether eating certain dietary fats can increase the production of beneficial fats (cyclopropane fatty acids) by gut bacteria in 10 healthy adults. Researchers measured these fats in blood, urine, and stool after a meal to see if the approach works. The goal is …

This study looked at whether eating a special type of sweet orange ('Rosy Red Valencia') that is rich in certain nutrients (carotenoids) can reduce inflammation and oxidative stress in healthy adults. Twenty healthy men and women ate either the special orange or a regular orange …

This study looked at how different supplements—collagen with vitamin C, whey protein, or a placebo—affect collagen production in the body after exercise. Twenty healthy adults took the supplements before doing short jump rope sessions three times in 24 hours. Researchers measured…

This study tested whether a small plastic cap called Endocuff Vision, placed on the tip of a colonoscope, helps doctors find more precancerous polyps (sessile serrated adenomas) during routine colon cancer screening. About 427 adults getting a screening colonoscopy were randomly …

This study used advanced total-body PET scans to compare lung function in 13 COVID-19 patients and healthy volunteers. Researchers measured how well the lungs' blood-air barrier worked, and checked for changes 4 months later. The goal was to learn more about how COVID-19 affects …

This study looked at how much of the numbing drug lidocaine gets into brain tumors during surgery for glioblastoma, an aggressive brain cancer. Researchers measured lidocaine levels in the blood and tumor tissue of 12 patients. The goal was to gather information that could help d…

This study looked at whether a personalized home exercise program could improve muscle function in people with moderate-to-severe chronic kidney disease who are not on dialysis. 32 participants were randomly assigned to either exercise training or health education. The goal was t…

This study looked at whether placing stitches 1 centimeter apart or 2 centimeters apart leads to a better-looking scar after surgery. Fifty adults had their wounds closed with both spacing methods on different parts of the same wound. Blinded reviewers then rated the scars to see…

This early study tested a new PET/CT imaging agent in 5 adults who had recovered from COVID-19. The goal was to see if the tracer could detect lung damage caused by the virus. Participants had no prior lung disease and needed two negative COVID tests before each scan. The study w…

This study tested a program for adults aged 65-90 who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is practical and hel…

This study looked at whether protein powders made from insects (IPC80 and whole buffalo powder) can turn on muscle-building processes in the body. Twenty healthy adults took a single dose of insect protein or whey protein, and researchers measured how their blood affected muscle …

This study looked at how drinking orange juice compared to a sugary drink affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugar-sweetened beverage for four weeks. Researchers measured changes in cholesterol, blood sugar …

This study looked at whether sending text messages to smokers could get them to call a quitline for free help. Over 4,000 patients from a large health system were sent texts offering either free counseling or free nicotine patches. The goal was to see which offer led more people …

This study tested a new type of PET scan to see if it could detect whether targeted therapy for genitourinary cancer (like kidney cancer) is working within days or weeks, instead of months. Eleven patients were scanned before and after starting treatment. The goal was to see if e…

This study looked at whether using telemedicine (video or phone calls) helps people with hard-to-heal leg wounds in rural areas see a specialist faster than going in person. About 116 adults with leg ulcers from conditions like diabetes or poor blood flow took part. Researchers m…

This study looked at how changing the ventilator's air volume and pressure during surgery affects pressure inside the lungs and chest. Researchers used a small balloon placed in the esophagus to measure these pressures in 150 adults having elective surgery. The goal was to better…

This study used a special full-body PET scanner to watch how a radioactive sugar moves through head and neck cancer and radiation-caused inflammation over time. Seven adults with stage II-IVa oral cancer took part after completing radiation therapy. The goal was to learn more abo…