University Of California, Davis

This study looks at two ways to deliver antibiotics directly into the breast pocket after tissue expander breast reconstruction to prevent infections. About 100 women will be randomly assigned to receive either a non-absorbable disc or absorbable beads, both releasing antibiotics…

This study tests new ways to help people with opioid use disorder stay on their buprenorphine medication after starting it in the emergency department. About 3,500 adults will take part across multiple hospitals. The goal is to see if better coordination between the ER and outpat…

This study looks at whether a simple vaginal swab test, called ROM-Plus, can quickly sort patients with pregnancy of unknown location and vaginal bleeding into high or low risk for ectopic pregnancy. About 122 English-speaking adults who are stable and have this condition will ta…

This study compares two needle devices used to take tissue samples from pancreatic lesions during an endoscopic ultrasound. The goal is to see which device provides better quality samples for diagnosis with fewer needle sticks. About 30 adults with pancreatic lesions will be rand…

This study looks at ways to make steroid injections into the knee less painful for people with osteoarthritis. Researchers will test if using a smaller needle or a cooling spray (ethyl chloride) reduces pain during the injection. About 88 adults with knee osteoarthritis will take…

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can help mothers of premature or sick babies in the NICU produce more breast milk. Forty mothers will receive either the supplement or a placebo, and researchers will measure milk volume and…

This study looks at whether acupuncture can help people with chronic low back pain caused by myofascial pain syndrome (muscle knots). Sixty-four adults will receive either real or fake (sham) acupuncture for eight weeks. Researchers will use full-body PET/CT scans to see if chang…

This study tests whether a topical solution of timolol, a drug usually used for glaucoma, can help surgical wounds heal faster when they are left to close naturally (without stitches). About 220 adults who have had skin cancer removal surgery will either apply timolol or a standa…

This study tests whether a rapid form of brain stimulation called accelerated iTBS can reduce depression symptoms in adults. Over 5 days, participants receive 50 sessions of either real or sham (placebo) stimulation. Researchers also use brain scans, blood tests, and a mobile app…

This study tests a new way to fix hernias using a needle guided by ultrasound, avoiding large cuts or general anesthesia. It is for adults who cannot or do not want standard surgery. About 30 people will be followed for 8 months to see if the procedure is safe and improves qualit…

This study tests a special sleeve worn on the lower belly that uses body heat to release energy waves and negative ions, aiming to increase blood flow and reduce pain. Researchers will compare it to a placebo sleeve in 100 women aged 18-45 who have regular menstrual cramps. The g…

This study tests whether a mobile app that uses AI and game-like features can help young adults (ages 18-24) who face food insecurity make healthier food choices. About 114 UC Davis students will use either a basic food-tracking app or a version with extra nudges and rewards for …

This study tests whether a sensitive blood test (ctDNA) can help doctors decide the best treatment for people with early-stage rectal cancer. About 200 participants will either have standard treatment or have their treatment guided by the blood test results. The goal is to see if…

This study tests a mobile health program called FANS-EI that aims to support caregivers of young autistic children in engaging with early interventions. Researchers will measure how comfortable and involved caregivers feel, as well as their sense of support and confidence. The st…