University Of Aarhus

This study tests whether using a fluorescent dye called indocyanine green during surgery helps surgeons see and remove all sarcoma tissue, reducing the chance that cancer cells are left behind. About 90 adults with intermediate-to-high grade sarcoma of the trunk or limbs will tak…

This study tests whether finding and treating bleeding early with blood transfusions can lower the risk of delirium (sudden confusion) in people 75 and older with hip fractures. About 198 participants will be randomly assigned to either early treatment or standard care. They will…

This study tests whether giving only aspirin before a heart procedure is as effective and safer than giving aspirin plus an extra blood thinner (fondaparinux) in people with a certain type of heart attack (NSTEMI). About 5,000 participants will be randomly assigned to one of the …

This study looks at whether opening narrowed kidney arteries with a small balloon and stent, plus standard medications, works better than medications alone for high-risk patients. About 80 participants with severe kidney artery narrowing and either hard-to-control high blood pres…

This study tests whether nurse-led telehealth support helps people with gout stick to their medication and keep uric acid levels under control. About 200 adults from Denmark who already take gout medication will be randomly assigned to either receive extra nurse support (via app,…

This study looks at children aged 5 to 14 who take medicine for urinary incontinence (like bedwetting) and are ready to stop. It compares stopping the medicine all at once versus slowly tapering off, to see which method lowers the chance of symptoms coming back. The goal is to fi…

This study looks at whether DNA markers in urine, vaginal, and cervical samples can accurately detect endometrial cancer in women with postmenopausal bleeding. Researchers will compare these tests to the standard ultrasound method. The goal is to find a less invasive way to ident…

This study aims to see if a special MRI machine designed for teeth and jaws can diagnose conditions like jaw joint disorders, tooth infections, and gum disease as well as or better than traditional X-rays. About 470 adults who need dental imaging for these issues will receive bot…

This study explores whether DNA testing on urine and vaginal samples collected by patients themselves can accurately detect endometrial cancer. Researchers will compare samples from 120 women—half with endometrial cancer and half healthy—to see if the test can tell them apart. If…

This study looks at whether adding an MRI scan to the usual CT scan helps doctors choose the best treatment for people with pancreatic cancer. About 200 patients who are initially thought to be candidates for surgery will be randomly assigned to get either a CT scan alone or a CT…

This study is testing whether offering liver cancer screening every 6 months to people with cirrhosis can reduce deaths from liver cancer. The screening includes an ultrasound and a blood test. About 617 adults aged 40-79 with compensated cirrhosis in one region of Denmark will b…

This study tests whether a therapist-guided exercise program helps people aged 50 and older recover better from a wrist fracture compared to usual care advice. About 588 participants will either receive supervised exercise sessions plus usual care, or usual care alone. The main g…

This study tests a new digital follow-up program for people who have had early-stage colorectal cancer. The program uses a smartphone app to monitor symptoms, fear of cancer returning, and quality of life, and provides personalized care. About 400 participants will be split into …

This study looks at whether combining two common therapy techniques—changing negative thoughts and practicing detached mindfulness—works better than using them alone for people with anxiety or depression. About 93 adults will be randomly assigned to different treatment combinatio…

This study tests whether a supplement called tributyrin can help lower blood sugar and reduce appetite in people with overweight or obesity. Twelve participants will take either tributyrin or a placebo for two weeks, then switch. Researchers will measure blood sugar, hunger, and …

This study tests a new way to plan radiation therapy for advanced lung cancer. Doctors will use a special scan (SPECT/CT) to see which parts of the lung work best, then aim radiation away from those areas to reduce side effects like coughing and shortness of breath. About 90 peop…

This study looks at whether adding progressive resistance training to a patient education program helps people with hip osteoarthritis move better and feel less pain. 150 adults with hip OA will be randomly assigned to either education plus exercise or education alone. Researcher…

This study looks at whether a 12-week progressive resistance exercise program can help reduce chronic pain in people with multiple sclerosis. Researchers will compare a group that exercises to a waitlist group that continues usual care. The goal is to find a drug-free way to mana…

This study tests a short form of talk therapy called Focused Acceptance and Commitment Therapy (FACT) for people with anxiety, depression, or stress. Sixty adults will either receive up to 250 minutes of FACT right away or wait 4 months before treatment. The goal is to see if FAC…

This study tests if fecal microbiota transplantation (FMT) can help people with diarrhea and colitis caused by immune checkpoint inhibitors, a type of cancer immunotherapy. About 20 adults with melanoma or kidney cancer will receive either FMT capsules or placebo capsules alongsi…

This study tests if combining two drugs (solifenacin and mirabegron) at low doses works better than high doses of either drug alone for children aged 5 to 14 with overactive bladder and daytime wetting. About 236 children who did not fully respond to low-dose treatment will be as…

This study looks at how well spinal cord stimulation works for people with long-term pain. About 25 adults who already have a spinal cord stimulator will rate their pain with the device on and off. The goal is to see if the stimulation truly reduces pain compared to a placebo eff…

This study tests whether a program of exercise and patient education can reduce hip and groin pain in people with hip dysplasia compared to usual care. About 200 adults with confirmed hip dysplasia and at least three months of pain will take part. The main goal is to see if pain …

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial weakness after a first-time stroke. Researchers will measure changes in facial symmetry using video recordings. The trial aims to recruit 130 adul…

This study looks at how your internal body clock changes the way you experience time when you stay awake for 36 hours. Healthy adults aged 23 to 45 will stay in a controlled lab, awake the whole time, with everything kept constant. Every two hours, they will do short tests on tim…

This study is a Danish national registry that will follow 160 patients with resistant high blood pressure caused by narrowed kidney arteries. Participants will undergo a procedure called percutaneous transluminal renal angioplasty (PTRA) to open the narrowed arteries. The main go…

This study follows 100 children with acute lymphoblastic leukemia (ALL) to see how the steroid dexamethasone moves through their blood and spinal fluid, and whether it affects bone density or causes nerve side effects. Participants continue their standard treatment and provide ex…

This observational study looks at whether a combination of treatments can reduce how much oxygen the heart and kidneys need in people with type 1 diabetes. About 40 adults with long-standing diabetes will be followed for two years. Researchers will use special scans and lab tests…

This study looks at whether a simple procedure called membrane sweeping, done several times near the end of pregnancy, can help labor start on its own before 41 weeks and 3 days. About 1,500 pregnant women will be randomly assigned to receive either no sweeping or up to three swe…

This study looks at how the body responds to glucagon, a hormone that helps control blood sugar and fat burning, in people with type 2 diabetes. Researchers want to see if glucagon resistance is linked to fatty liver disease and heart problems. About 24 adults with type 2 diabete…

This study looks at how blood sugar levels change throughout the day in pregnant women with gestational diabetes. Researchers will use a continuous glucose monitor for 14 days to track patterns and see how they relate to the baby's growth and birth weight. The goal is to better u…

This study looks at new ways to detect if vulva cancer has come back after treatment. Researchers will ask 295 women to fill out surveys every four months and give blood samples to look for cancer DNA. They will compare results with a group of 1000 women treated in the past. The …

This study aims to find out which of two common blood pressure drugs, noradrenaline or phenylephrine, is better at keeping blood flowing to the brain and other organs during brain surgery. Researchers will measure blood flow and oxygen use in the brain using a special scan. The s…

This study looks at how often blood vessel problems happen after a kidney transplant and whether a balloon treatment can help. Researchers will follow 60 kidney transplant patients in Denmark to check kidney function and blood pressure. The goal is to find better ways to diagnose…

This study watches 250 adults who are unconscious after a cardiac arrest to find early signs that predict when they will wake up. Researchers use brain wave tests, eye exams, and ultrasound to gather clues. The goal is to help doctors better understand recovery, not to test a new…

This study looks at better ways to monitor giant cell arteritis, a condition that causes inflammation in arteries and can lead to blindness or aneurysms. Researchers will use ultrasound scans and patient questionnaires to see if they can predict when the disease will flare up. Up…

This study is collecting information from 500 people who need a second round of high-dose radiation for lung or other chest cancers. The goal is to learn how to give this treatment more safely by tracking side effects and survival. Researchers hope the findings will help doctors …

This study looks at whether vaginal estrogen treatment changes blood clotting in postmenopausal women with vaginal atrophy. Researchers will take blood samples before and after 3 months of treatment to measure various clotting factors. The study includes 90 women, some with a his…

This study looks at how a small, daily time delay (like shifting your schedule by one hour each day) changes your internal body clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples living in a lab for five days. The goal is to understand time …

This study looks at whether a simple blood test after surgery for colorectal cancer can better predict if the cancer will come back. About 1,600 patients will give blood samples to check for leftover tumor DNA. If successful, this test could help doctors decide who really needs c…

This study looks at how being a morning person or a night owl changes the way you experience time. Healthy adults aged 23 to 45 who are clearly one type or the other will do computer tasks at their best time and at their worst time. The goal is to see if time judgments and alertn…

This study watches how breathing support (ventilation) is given during CPR to adults whose hearts stop in the hospital. Researchers want to find which breathing rate and volume gives the best chance of restarting the heart. The study will track 900 patients and compare different …

This study aims to see how consistently people with bipolar disorder take their lithium medication in real life. About 50 participants will use a special pillbox that records the time they take their pill each day for 4 weeks. Researchers will also call them weekly to compare wha…

This study follows 250 people with chronic diverticular disease to see if elective surgery improves their quality of life compared to those who continue with conservative treatment. Participants will fill out questionnaires about their symptoms and well-being. The goal is to help…

This study looks at how different sex hormone levels in women affect muscle growth from physical training. Researchers will measure changes in muscle mass, fat, and tendons in 60 women with natural cycles, hormonal IUDs, or hormonal contraception. The goal is to understand how ho…

This study looks at how ketone bodies—chemicals your liver makes when you fast or exercise—affect how your body uses energy and responds to insulin. Ten overweight adults aged 55–70 will each try four different treatments (including a ketone drink and a placebo) on separate days.…

This study looks at how the mind and body respond to migraine treatments, including placebos. Researchers will give 60 adults with chronic migraine four different treatment conditions in random order. The goal is to better understand how expectations and side effects influence tr…

This study aims to understand the sexual health challenges and needs of bladder cancer patients, and to develop a support program. Researchers will interview 30 patients to learn about their experiences and preferences. The goal is to create a program that helps patients and thei…

This study aims to understand what happens inside the tissue after a leg amputation above the knee. Researchers will use a tiny probe (microdialysis) to measure chemicals related to blood flow, inflammation, and antibiotics in the stump. The study includes 20 adults with and with…

This study looks at how the way treatment information is given affects how well migraine medication works and what side effects people notice. Researchers will give 128 adults with episodic migraine six different treatments in a random order to compare drug effects, placebo effec…

This study aims to find out if spinal cord stimulation (SCS) truly reduces pain or if the effect is just due to patients' expectations. 25 adults with chronic pain who already have an SCS implant will take part in four test sessions where the device is turned on or off without th…

This study looks at how often people with Crohn's disease, ulcerative colitis, an ileostomy, or bile acid diarrhea have low magnesium levels. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. Researchers will compare dif…