New study: could a simple drain cut hospital time for lung abscess patients?

NCT ID NCT07247461

Disease control Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether placing a small tube through the chest wall to drain pus from a lung abscess, along with standard antibiotics, helps people recover faster and leave the hospital earlier. About 84 adults with large abscesses will be randomly assigned to get either the drainage procedure plus antibiotics or antibiotics alone. The main goal is to see if the drainage group has shorter hospital stays.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Aug 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>18 years. * Signed informed consent. * CT scan compatible with LA (one or more cavitating lesions with liquid content). * Clinical findings suggestive of ongoing infection. * Lung abscess size ≥ 4 cm in diameter. * Imaging indicates that the abscess contains fluid. * The abscess involves the outer one-third of the lung. Exclusion Criteria: * Pregnancy. Prior to inclusion of fertile women, a negative pregnancy test must be available. * Brest feeding. * Predicted survival of less than 3 months. * Known tuberculosis or non-tuberculous mycobacteriosis. * Known chronic pulmonary aspergillosis. * Patients with a primary suspicion of lung cancer * Recent (\<3 months) contact with health facilities outside Scandinavia. * Patients in whom anticoagulant treatment cannot be discontinued, or in whom the treatment pause does not allow drainage within 72 hours. * Coagulopathy or other increased bleeding risk that cannot be corrected to allow drainage within 72 hours. * Hemodynamic and/or respiratory unstable patient.

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Conditions

The condition(s) this trial relates to.

lung abscess

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung abscess

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

New study: could a simple drain cut hospital time for lung abscess patients?

What the study statuses mean