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New biomarker test could spare patients unnecessary lung biopsies

NCT ID NCT01085864

Diagnosis Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks for markers in blood, sputum, or urine that can help doctors decide if a lung nodule found on a CT scan is cancerous or harmless. The goal is to reduce the need for invasive biopsies. Researchers will also check if these markers return to normal after successful cancer surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 550 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2010

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients being evaluated by CT Scan with Lung Nocules

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult 18-85 years of age 2. Patients referred to pulmonologists, oncologists, or thoracic surgeons for the evaluation of peripheral lung nodules found on CT scan. 3. Repeat CT scans, biopsy or surgical excision are clinically indicated to determine the etiology of the nodule. 4. One or more lung nodules must be between 8 mm and 30 mm in the greatest diameter. 5. Patients must be fully informed of the investigational nature of the procedure and sign an informed consent. \- Exclusion Criteria: 1. Lung nodules or masses greater than 30 mm in the greatest dimension. 2. Lung nodules that have solid calcification. 3. Lung nodules or masses with CT evidence of partial or complete obstruction of a lobar bronchus, main stem bronchus or the trachea. 4. No prior cancer with the exception of non-melanoma skin cancer. 5. Life expectancy of \< 6 months 6. Any individual who does not give oral and written consent for participation -

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Conditions

The condition(s) this trial relates to.

lung abscess

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung abscess

Contacts and locations

Locations

  • University of Colorado Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.