Seoul National University Hospital
Clinical trials sponsored by Seoul National University Hospital, explained in plain language.
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Heart attack patients may get safer treatment with lower drug dose and new stents
Disease control CompletedThis study tested two things in over 3,400 people who had a heart attack and needed a stent: whether newer stents that dissolve over time work as well as permanent ones, and whether a lower dose of the blood thinner prasugrel is as safe and effective as the standard dose. The goa…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 26, 2026 03:29 UTC
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Incompatible kidney transplants boost survival in elderly patients
Disease control CompletedThis study looked at 1,819 elderly patients (age 60+) with end-stage kidney disease to see if receiving a kidney from a living donor that was not a perfect match (ABO- or HLA-incompatible) helped them live longer compared to waiting for a compatible deceased donor kidney. The res…
Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 26, 2026 03:28 UTC
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Promising combo tackles relapsed lymphoma
Disease control CompletedThis study tested a combination of two drugs, bendamustine and rituximab, in 27 adults with a type of blood cancer called marginal zone B-cell lymphoma that had come back or worsened after prior treatment. The goal was to see how many patients' tumors shrank or disappeared. The t…
Phase: PHASE2 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 26, 2026 03:27 UTC
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Which blood thinner wins after stents? major trial reveals answer
Disease control CompletedThis study looked at over 5,500 people with coronary heart disease who had a drug-coated stent placed. After taking two blood thinners for about a year, they were switched to either clopidogrel or aspirin alone. The goal was to see which single drug better prevents heart attacks,…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 26, 2026 03:24 UTC
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Heart stent showdown: which Drug-Coated device and blood thinner plan works best?
Disease control CompletedThis study tested two different drug-coated stents (everolimus-eluting vs. sirolimus-eluting) in 1,466 people with narrowed heart arteries. It also compared taking the blood thinner clopidogrel for 6 months versus 12 months after stent placement. The goal was to see which stent k…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New electrode combo shows promise for stubborn liver cancer
Disease control CompletedThis study tested an improved heat-based treatment (radiofrequency ablation) for liver cancer that came back after a standard procedure. 100 adults with one to three small tumors received the treatment using special twin electrodes. The goal was to see how well the new method con…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Shingles vaccine shows promise for HIV patients in new study
Disease control CompletedThis study looked at how well the shingles vaccine works and if it's safe for people living with HIV. Researchers compared immune responses based on participants' CD4+ T-cell counts and age. A total of 71 adults with HIV who were on stable antiviral treatment took part. The goal …
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Immunotherapy after Chemo-Radiation shows promise for nasopharyngeal cancer
Disease control CompletedThis study tested whether adding the immunotherapy drug pembrolizumab after standard chemoradiation helps control advanced nasopharyngeal cancer. 53 patients received up to 17 cycles of pembrolizumab over about a year. The main goal was to see how many patients remained cancer-fr…
Phase: PHASE2 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Can a Low-Dose statin still pack a punch against high cholesterol?
Disease control CompletedThis study looked at whether a low dose (10 mg) of the statin drug rosuvastatin can effectively lower LDL cholesterol in Korean adults who need cholesterol-lowering therapy. Researchers enrolled 242 participants with different risk levels, including those with heart disease, very…
Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Promising combo tackles rare lung cancer
Disease control CompletedThis study tested a combination of the immunotherapy drug durvalumab with two chemotherapy drugs (doxorubicin and ifosfamide) in 16 people with a rare and aggressive type of lung cancer called pulmonary sarcomatoid carcinoma. The goal was to see if the combo could shrink tumors a…
Phase: PHASE2 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Heart stent showdown: which Drug-Coated device wins?
Disease control CompletedThis study looked at two types of stents (small mesh tubes) used to open blocked heart arteries. Over 3,000 people received either a newer everolimus-coated stent or an older sirolimus-coated stent. Researchers tracked heart attacks, deaths, and the need for repeat procedures to …
Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Double antenna microwave zaps liver tumors more precisely
Disease control CompletedThis study tested a new way to treat small liver cancer using microwave ablation with two antennas at once, instead of the usual single antenna. Twenty adults with early-stage liver cancer took part. The goal was to see if the two-antenna method could completely destroy tumors wi…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Heart surgery sedative may shield the heart from damage
Disease control CompletedThis study tested whether dexmedetomidine, a sedative that preserves breathing better than other drugs, can protect the heart during cardiac bypass surgery. Researchers measured heart damage in 224 adults undergoing heart surgery with a heart-lung machine. The goal was to see if …
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Your voice could reveal swallowing trouble: new study
Diagnosis CompletedThis study collected voice recordings and sensor data from 259 adults with swallowing difficulties. The goal was to see if changes in voice can accurately detect swallowing problems, like food or liquid going into the airway. Researchers compared voice tests with a standard X-ray…
Sponsor: Seoul National University Hospital • Aim: Diagnosis
Last updated May 26, 2026 03:29 UTC
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New breathing mask may make gallbladder surgery safer and faster
Symptom relief CompletedThis study tested whether a video laryngeal mask (a type of breathing tube) works better than the standard endotracheal tube for people having gallbladder surgery. 102 adults were randomly assigned to one of the two methods. Researchers measured how long it took to insert the tub…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:30 UTC
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Could a pinch of radiation soothe aching knees?
Symptom relief CompletedThis study tested whether a very low dose of radiation therapy can safely reduce pain and improve knee function in people with knee osteoarthritis. 114 adults aged 50-85 with moderate knee arthritis took part. The main goal was to see if more participants reported significant pai…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:29 UTC
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Smartwatch boosts CPAP use in sleep apnea patients
Symptom relief CompletedThis study tested whether using a smart watch and its companion app could help people with obstructive sleep apnea use their CPAP breathing machine more consistently. 46 adults who had trouble sticking with CPAP therapy took part. The goal was to see if the extra health tracking …
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:26 UTC
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Which pain block works best for kids after bone graft surgery?
Symptom relief CompletedThis study looked at 40 children aged 7 to 17 who needed bone graft surgery for their jaw. Doctors compared two ultrasound-guided pain-block methods to see which one reduced pain and the need for strong pain medicine better in the first 24 hours after surgery. The goal is to find…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:26 UTC
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VR games show promise for stroke arm recovery
Symptom relief CompletedThis study tested whether playing virtual reality games with a headset could help people who had a stroke more than 6 months ago improve arm and hand function. Fifteen chronic stroke patients with arm weakness participated. The results will show if this fun, immersive approach ca…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:25 UTC
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Ear zaps curb cravings: new Drug-Free way to eat less?
Symptom relief CompletedThis study tested a wearable ear device that sends gentle electrical pulses to a nerve to help control appetite. Sixty healthy adult women each had two visits: one with the device on and one with it off. Researchers measured how much they ate, their hunger levels, and food cravin…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:24 UTC
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Shockingly simple: headset may ease Parkinson's walking woes
Symptom relief CompletedThis study tested a safe, self-administered brain stimulation technique (transcranial direct current stimulation) to see if it could improve walking in people with Parkinson's disease. Twenty-four participants used the device at home while performing walking tasks, both alone and…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:15 UTC
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Heart drug may boost stamina in stented patients
Symptom relief CompletedThis study looked at whether amlodipine, a blood pressure medicine, can help people with stented heart arteries exercise longer and use less chest pain medication. About 211 stable angina patients with narrowed arteries took part. The goal was to see if amlodipine improves oxygen…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:14 UTC
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Timing pain meds before surgery could slash opioid need
Symptom relief CompletedThis study looked at 154 men having robot-assisted prostate removal. It compared giving a combination of acetaminophen and ibuprofen before surgery versus right after, to see which approach reduces the need for strong opioid painkillers. The goal is to manage pain with fewer opio…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:04 UTC
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Deep relaxation may shield Kids' hearts during eye surgery
Symptom relief CompletedThis study looked at 201 children aged 3 to 18 having strabismus (crossed eyes) surgery. Researchers tested whether giving a deeper level of muscle relaxant during anesthesia could prevent a sudden, dangerous drop in heart rate called the oculocardiac reflex. The goal was to make…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:04 UTC
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VR headsets take on workplace stress: study tests chill factor
Symptom relief CompletedThis study looked at whether a virtual reality (VR) experience can help healthy workers recover from stress faster. Sixty adults were randomly assigned to either a VR session or a control group after a stress-inducing task. Researchers measured stress using saliva samples and sel…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Natural compound icariin tested for acne and scar reduction
Symptom relief CompletedThis study tested whether a cream made from icariin, a plant extract, can improve acne and reduce acne scars. 25 adults applied the cream to one side of their face and a control solution to the other side twice daily for 2 months. Researchers counted acne lesions and scars and to…
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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New study aims to prevent breathing problems in obese patients during joint surgery
Symptom relief CompletedThis study looked at 110 obese patients having knee or hip replacement surgery under spinal anesthesia. Researchers compared two ways to calculate the dose of a sedative called remimazolam: one based on ideal body weight and one on total body weight. The goal was to find which do…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Antibody levels may predict kidney transplant rejection
Knowledge-focused CompletedThis study looked at 241 kidney transplant patients to see how certain antibodies (AT1R-Ab) change before and after transplant. Researchers measured antibody levels over one year to understand their link to kidney function and rejection. The goal is to help doctors better predict…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:30 UTC
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Massive stent registry reveals Real-World performance
Knowledge-focused CompletedThis study looked at over 17,000 people with coronary artery disease who received drug-eluting stents (tiny mesh tubes coated with medicine) to open blocked heart arteries. Researchers compared different types of stents to see how well they worked and how safe they were over the …
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:26 UTC
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Can a quick blood pressure check match continuous monitoring during surgery?
Knowledge-focused CompletedThis study looked at 258 adults having non-cardiac surgery to see if checking blood pressure every minute with a standard cuff works as well as using a continuous artery line to prevent low blood pressure during anesthesia start. The goal was to find out if the simpler method is …
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:23 UTC
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New study reveals hidden risks of common IV catheters in kids
Knowledge-focused CompletedThis study looked at 48 children who received a midline catheter during surgery to find out how often problems like infection, bleeding, or blockages happen. Researchers checked the catheter site right after placement, 24 hours later, and before removal. The goal is to identify w…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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Nutrition blood test may forecast brain surgery outcomes
Knowledge-focused CompletedThis study explored whether a nutritional score called PNI (Prognostic Nutritional Index) can predict how well patients do after brain tumor surgery. Researchers looked back at records from over 3,200 adults who had brain tumor surgery at a major hospital in South Korea. They che…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Brain waves track surgery stress in new study
Knowledge-focused CompletedThis study looked at how brain activity (EEG) and stress hormones change when patients are put to sleep and have a breathing tube placed or an incision made during abdominal surgery. Researchers monitored 52 adults undergoing open abdominal surgery to see if these two measures ar…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Could sleep apnea worsen lung cancer in non-smokers?
Knowledge-focused CompletedThis study looked at 77 never-smokers newly diagnosed with lung cancer to see how many also have sleep apnea and whether sleep apnea affects their cancer outlook. Participants had a sleep test before starting cancer treatment. The goal is to understand if sleep apnea is linked to…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:49 UTC
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Breathing tube pressure linked to sore throat after surgery
Knowledge-focused CompletedThis study looked at 337 people having laparoscopic surgery to see if the pressure in their breathing tube during the operation affected whether they had a sore throat afterward. Researchers measured how long the pressure was too high and checked for sore throats 1 and 24 hours a…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Heart study probes blood flow after balloon procedure
Knowledge-focused CompletedThis study looked at 43 people with stable coronary artery disease who needed a balloon procedure to open blocked heart arteries. Researchers measured blood flow right after the procedure to see how different balloon types (scoring vs. regular) affected results. The goal was to b…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC