Seoul National University Hospital

This study tests whether women with breast cancer whose armpit lymph nodes appear cancer-free on ultrasound after chemotherapy can safely avoid surgery to remove those nodes. Half the participants will skip armpit surgery, while the other half will have the standard sentinel node…

This study tests whether the drug letermovir can prevent serious CMV infections in people with relapsed/refractory multiple myeloma who are being treated with elranatamab. CMV is a common virus that can cause severe illness in patients with weakened immune systems. The study will…

This study looks at whether people with well-controlled gout (for 5 years or more) can take a lower dose of febuxostat or even stop it without their uric acid levels rising or symptoms coming back. About 59 adults will be split into three groups: one that reduces the dose, one th…

This study tests whether the drug maribavir can safely lower levels of cytomegalovirus (CMV) in people with blood cancers like lymphoma or multiple myeloma who are receiving bispecific antibody therapy. About 20 adults will receive maribavir, and researchers will measure how many…

This study checks the long-term safety and effectiveness of a one-time stem cell treatment for rotator cuff disease. It follows 21 people who already received the stem cells in an earlier trial. Researchers will measure shoulder pain and function over time using standard question…

This study tests whether adding a trastuzumab biosimilar (SB3) to the chemotherapy drug eribulin helps control advanced HER2-positive breast cancer better than eribulin alone. It is for people whose cancer has returned or spread and who have already tried at least two prior HER2-…

This study tests a faster way to treat small liver cancers (up to 5 cm) using tiny radioactive beads called Y90 resin microspheres. Normally, doctors do a pre-treatment scan to check where the beads will go, but this study skips that step for patients who meet certain safety crit…

This study tests a new way to pace the heart in people with heart failure whose heart pumps less blood than normal. The method, called left bundle branch area pacing, may help when standard pacing doesn't work. Researchers will check how well it works and how safe it is in 200 ad…

This study tests whether giving fluids during surgery based on each child's heart function can lower the risk of temporary stroke-like episodes after Moyamoya disease surgery. About 94 children under 18 will be randomly assigned to either personalized fluid management or standard…

This study tests a new microwave device to treat small liver cancers (up to 4 cm). Doctors will use imaging to guide the device and destroy the tumor plus a small safety margin. The goal is to see how often the tumor is fully treated and how many cancers come back within one year…

This study tests whether the drug clopidogrel can prevent major heart problems and strokes in people who have early, non-blocking plaque in their heart arteries. About 11,000 adults aged 40 and older with plaque found on scans but no current symptoms will take either clopidogrel …

This study tests a new, faster method to treat paroxysmal atrial fibrillation (a type of irregular heartbeat). Doctors will use a very high power, short duration energy to isolate the veins in the heart. The goal is to see if this approach reduces procedure time while still being…

This study tests whether a same-day procedure using Y90 resin microspheres is safe and feasible for people with large liver tumors (over 5 cm). About 138 participants will receive planning angiography, a scan, and treatment all in one day. The goal is to confirm that this approac…

This early-phase study tests whether stem cells from donated umbilical cords can safely help people with long-lasting shoulder pain from rotator cuff disease. About 21 adults who haven't gotten better with standard treatments will receive the stem cell injection. The goal is to s…

This study tests whether a combination of two drugs, venetoclax and decitabine, can help adults with T-cell acute lymphoblastic leukemia or lymphoma that has come back or not responded to standard treatment. About 28 participants aged 19 to 79 will receive this modified chemother…

This study compares two approaches to taking blood thinners after a procedure for atrial fibrillation (an irregular heartbeat). One group takes blood thinners every day as usual. The other group takes them only when a small heart monitor detects that the irregular rhythm has retu…

This study compares two catheter ablation methods for people with persistent atrial fibrillation (AFib). One method only isolates the pulmonary veins, while the other also targets scar tissue in the left atrium. The goal is to see which approach better prevents abnormal heart rhy…

This study tests a 12-week remote cardiac rehabilitation program for children aged 8 to 18 with complex congenital heart disease. Participants exercise at home using apps or video platforms, and researchers measure changes in heart-lung fitness and quality of life. The goal is to…

This study tests whether bortezomib, a drug used for certain cancers, can safely raise platelet counts in adults with immune thrombocytopenia (ITP) that has come back or not responded to standard treatments. About 29 participants will receive the drug, and researchers will check …

This study compares two approaches for people with a weak heart caused by blocked arteries: a procedure to open blockages (PCI) plus medication versus medication alone. Researchers want to see which better helps the heart pump blood. About 158 adults with low heart function and m…

This study is testing a new ultrasound-based method called DeepUSFF to measure liver fat in people with fatty liver disease. Researchers will compare the ultrasound results to MRI scans, which are the current gold standard. The goal is to see if the simpler, cheaper ultrasound ca…

This study looks at whether using a lower suction pressure on the chest tube after lung cancer surgery can help it come out sooner. About 160 adults having lung surgery will be randomly assigned to either the standard suction or a gentler setting. The goal is to see if the gentle…

This study tests whether a special swallowing exercise program can help people with multiple system atrophy (MSA) who have trouble swallowing. About 24 adults with MSA and swallowing problems will be randomly assigned to receive the therapy or usual care. The goal is to see if th…

This study tests a special fabric shoulder brace designed to mimic muscle action. Researchers want to see if it helps people with neuromuscular disorders (like muscular dystrophy or ALS) move their arms and hands better. About 30 participants will be evaluated with and without th…

This study tests if a special compression vest (called HUGgy) can help children aged 3 to 10 feel less agitated and confused after waking up from tonsil and adenoid surgery. Half the children will wear the vest in the recovery room, while the other half receive standard care. Res…

This study compares two pain medicines, sufentanil and remifentanil, given during brain bypass surgery. The goal is to see which one better prevents low blood pressure, a common complication. 92 adults having elective surgery will be randomly assigned to one of the two drugs, and…

This study looks at whether a set of enhanced recovery steps (called ERAS) can help people who have minimally invasive stomach cancer surgery meet discharge criteria sooner. About 308 adults will be randomly assigned to either standard care or the ERAS protocol. The goal is to se…

This study tests if a special numbing injection (nerve block) can reduce pain and the need for strong painkillers after ear surgery in teenagers aged 13 to 18. Half of the 60 participants will get the injection before surgery, and the other half will not. The main goal is to see …

This study looks at two methods of giving the sedative remimazolam during brain bypass surgery in people with Moyamoya disease. The goal is to see which method uses less total medicine. About 58 adults having this surgery will take part, and the results will help guide safer anes…

This study compares a new AI and ultrasound device (AIIV L2) to the standard manual method for drawing blood. About 190 adults will get blood drawn from both arms—one using the device, one manually—to see which is more successful on the first try, faster, and less painful. The go…

This study looks at whether choosing the left or right nostril for inserting a breathing tube affects the chance of a nosebleed. About 208 adults having planned surgery will take part. The goal is to find out if one side is safer, helping doctors reduce this common complication.

This study watches how drug-coated balloons change blood vessels in people with coronary artery disease. Researchers will use CT scans to measure blood flow and plaque before and after the procedure. The goal is to see how these changes relate to patient outcomes. About 165 adult…

This study will follow 1,000 people in Korea who are suspected of having sleep apnea. Researchers will track their symptoms, use of breathing machines, and long-term health outcomes to better understand the condition. Participants will have sleep tests and regular check-ups, and …

This study compares two ways to place a midline catheter (a type of IV) in children aged 2 to 17. One method uses the basilic vein, the other the cephalic vein. The goal is to see which approach allows easier blood draws and causes fewer complications. 96 children will take part …

This study watches 80 adults with a narrowed windpipe (subglottic stenosis) who are having airway surgery. Doctors use a special oxygen technique called THRIVE to keep patients breathing. The goal is to learn what factors predict when oxygen levels fall too low and extra breathin…

This study interviews 200 adults who had a near-death experience after serious medical events like cardiac arrest or ICU care. Researchers want to learn how common these experiences are and what people remember. The goal is to better understand these mysterious events, not to tes…

This study is observing how well double umbilical cord blood transplants work in Korean adults with blood cancers or bone marrow failure. Researchers will track survival, engraftment, and side effects like graft-versus-host disease. The goal is to gather real-world data to improv…

This study observes 100 people in Korea with advanced HER2-positive breast cancer who will receive the drug T-DM1 immediately after stopping T-DXd. The goal is to see how long the cancer stays under control with this treatment sequence. Researchers will track tumor scans and surv…

This study is tracking over 5,000 adults who had a cardiac arrest outside the hospital. Researchers want to find out what causes these events by looking at health habits and chronic diseases. They will also develop a prediction model and search for new biomarkers. The goal is to …

This study compares a new mixed reality (MR) system for learning CPR to standard instructor-led training. Researchers want to see if the MR method is just as effective at teaching CPR skills. The study will involve 120 adults aged 18-50 who haven't had CPR training in the last ye…

This study involves 30 adults with liver tumors who are scheduled for radioembolization, a treatment that delivers radiation directly to the tumor. Doctors want to see if using a small 'scout dose' of the actual treatment beads can more accurately measure how much radiation might…

This study watches 40 adults with atrial fibrillation who get a new heart procedure called pulsed field ablation. The goal is to see if tiny, symptomless spots appear on brain scans afterward. Researchers want to learn how safe this new technique is for the brain.