Seoul National University Hospital

This study tests whether transferring healthy donor stool into the gut (fecal microbiota transplantation) can safely improve symptoms and reduce steroid use in 30 people with mild-to-moderate ulcerative colitis. Participants aged 10–80 will be followed for 48 weeks to see if the …

This study looks at a new type of electrode used in radiofrequency ablation, a treatment that uses heat to destroy small liver cancers (up to 3 cm). The goal is to see if this new device can better control tumor regrowth and reduce damage to nearby organs. About 76 adults with li…

This study looks at how well a treatment called 90Y radioembolization works for people with early-stage liver cancer. About 200 patients in Korea will be followed to see how their tumors respond, how long they live, and what side effects occur. The goal is to gather real-world da…

This study tests a combination of two drugs, tislelizumab and pemetrexed, in 28 adults whose primary central nervous system lymphoma (a type of brain cancer) has returned or not responded to prior treatment. The goal is to see if the combination can shrink tumors and improve surv…

This study tests a new fluorescent clip that helps surgeons see exactly where a colon tumor is during minimally invasive surgery. About 110 adults with colon cancer will be randomly assigned to get either the clip or a standard dye injection before surgery. The goal is to see if …

This study aims to find the smallest effective dose of the numbing drug ropivacaine for a nerve block in the leg during diabetic foot surgery. Researchers will test different doses in 45 adults to see what works best for 90% of patients. The goal is to provide effective pain reli…

This study looks at how the area around a tumor changes during chemotherapy in people with HER2-positive breast cancer. Researchers will take samples before, during, and after treatment in 30 patients who are getting chemo before surgery. The goal is to understand these changes b…

This study tests if a video system can help parents provide early developmental therapy at home for very premature or very low birth weight infants with brain damage. A therapist monitors sessions twice a week via Zoom and reviews parent-recorded videos to adjust goals. The study…

This study is looking at whether having low muscle mass (sarcopenia) before lung cancer surgery affects how well patients recover. Researchers are following 400 older adults to see if muscle loss is linked to survival and cancer return. The goal is to find out if checking muscle …

This study tests whether virtual reality (VR) can train new doctors as well as high-fidelity simulation (using lifelike mannequins) for handling emergencies like severe allergic reactions and low oxygen levels. About 124 medical interns will be randomly assigned to one training m…

This study looks at why some lung cancers with a specific gene change (EGFR mutation) stop responding to the drug osimertinib. Researchers are analyzing the genetic makeup of tumors from 148 adults with advanced lung cancer to find resistance mechanisms. The goal is not to test a…

This study compares two devices used to place a breathing tube through the nose for ear, nose, and throat surgery. 74 adults will be randomly assigned to receive either a videolaryngoscope or a flexible bronchoscope. The main goal is to see which tool succeeds more often on the f…

This study looks at whether women with early-stage breast cancer (tumors under 5 cm) and no signs of cancer in lymph nodes on ultrasound can safely avoid sentinel lymph node biopsy during breast-conserving surgery. About 1,734 women are randomly assigned to either skip the biopsy…

This study was designed to see if a gentle brain stimulation technique called tDCS could help with negative symptoms (like lack of motivation or emotion) in people with schizophrenia. Researchers planned to use brain scans and electrical recordings to understand how it works. How…

This study looks at how the 'watch and wait' approach affects the quality of life of people with slow-growing lymphomas. Researchers want to know if waiting without treatment causes anxiety or worry. About 250 Korean adults with these cancers will fill out questionnaires to measu…

This study is collecting health information from 2000 people with Crohn's disease or ulcerative colitis to create tools that predict how well different treatments will work. The goal is to help doctors choose the right biologic or small-molecule drug for each patient. Participant…