Heart-Smart surgery: new approach may shield Kids' brains during moyamoya procedure
NCT ID NCT07304947
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a personalized approach to managing fluids during brain surgery for children with Moyamoya disease. Instead of standard blood pressure targets, doctors will use each child's baseline heart function to guide fluid delivery. The goal is to reduce temporary stroke-like episodes after surgery. About 94 children under 18 will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 94 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 month to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pediatric patients \<18 years undergoing EDAS for Moyamoya disease under general anesthesia Exclusion Criteria: * ASA physical status 4-5 * Emergency surgery * Known cardiovascular disease * Any condition judged inappropriate by investigators
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Seoul National University Children's Hospital
RECRUITINGSeoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Predicting the unpredictable: new model aims to forecast brain bleeds in moyamoya
- Can a daily pill and a simple physical therapy delay moyamoya strokes?
- Metaverse meets microsurgery: XR platform aims to sharpen brain bypass precision
- French biobank aims to unlock secrets of rare brain vessel diseases
- Your digital twin could help prevent another stroke
- Could a simple MRI and blood test predict moyamoya before it strikes?