Peking Union Medical College Hospital

This study is testing a treatment for chronic constipation that doesn't get better with usual medicines. Doctors will transplant healthy gut bacteria from a donor into patients, along with special fibers meant to help those good bacteria grow. The goal is to see if this combined …

This study is testing if giving a higher, more focused dose of radiation before surgery can better eliminate rectal cancer tumors. Researchers will compare the stronger radiation dose to the standard dose in 156 adults with locally advanced rectal cancer. The goal is to see if th…

This study is testing a small, hormone-releasing device placed in the uterus after an abortion to see if it helps the uterine lining heal better and faster. Researchers will compare it to a similar device without hormones. The goal is to see if the hormone version improves recove…

This early-stage study is testing a new inhaled therapy called BMD003 for cystic fibrosis (CF). The therapy delivers mRNA, a genetic instruction, to the lungs to help produce a needed protein. The main goals are to check if the treatment is safe and to look for early signs that i…

This early-stage study is testing a new radioactive drug called 161Tb-LNC1011 in men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. The main goals are to find a safe dose, see how the drug travels in the body, and look for early …

This study is testing if giving a cholesterol-lowering drug (a PCSK9 inhibitor) soon after a stroke can help people recover better. It will involve over 1,200 patients in China who have had a stroke caused by a narrowed brain artery. Half will get the drug as a single injection, …

This large study aims to see if adding one of two treatments to standard hospital care can help adults with severe pneumonia who are on breathing machines. Researchers will test whether lying patients in a specific head-down position or giving them a tailored herbal medicine form…

This study is testing whether combining two drugs, orelabrutinib and romiplostim, can help people with chronic immune thrombocytopenia (ITP) achieve better and longer-lasting control of their condition. It is for adults who have already tried at least one other treatment. The mai…

This study is testing whether using a special bedside scanner to personalize ventilator settings can help patients with Acute Respiratory Distress Syndrome (ARDS) survive and recover faster. Researchers will compare this personalized approach to standard ventilator care in 574 ad…

This study is testing whether adding a fourth drug (isatuximab) to the standard three-drug combination works better for people with high-risk multiple myeloma who cannot receive stem cell transplants. Researchers will compare the four-drug combination against the standard three-d…

This study is testing whether a medication called butylphthalide, taken for a full year, can help people who have just had a minor stroke. Researchers want to see if it prevents another stroke, reduces disability, and protects memory and thinking skills. About 1,200 participants …

This study is testing whether adding a specific Chinese herbal formula to standard ovulation therapy helps more women with diminished ovarian reserve get pregnant naturally. It will compare pregnancy rates between women receiving the combined treatment and those receiving standar…

This study is testing whether a traditional Chinese herbal formula, taken for several months before and during IVF treatment, can help women with low egg reserve get pregnant. Researchers will compare pregnancy rates between women taking the real herbal formula and those taking a…

This study is testing if a computer system that gives doctors real-time feedback can help them better protect the lungs of critically ill patients on breathing machines. It will compare the new alert system to standard ICU care in over 200 patients with severe breathing problems.…

This study aims to create a personalized management model for people with early-onset type 2 diabetes by combining Western medicine with Traditional Chinese Medicine. It will enroll 2000 adults diagnosed before age 40 to collect detailed health data, including blood sugar monitor…

This study is testing a pill called orelabrutinib for people with autoimmune hemolytic anemia (AIHA) whose disease has come back or hasn't responded to standard treatments. It will enroll 50 adults to find the best dose and see how well it works to control the disease over 12 to …

This study is testing an oral medication called Linprixel for adults with autoimmune hemolytic anemia that has come back or not responded to at least two prior treatments. Over 12 weeks, doctors will adjust the dose based on how well the patient responds and monitor for side effe…

This study is testing a smartphone app designed to help pregnant women with gestational diabetes control their blood sugar. The app provides personalized plans, tracks progress, and offers educational information to improve self-management. Researchers want to see if using this d…

This study is testing a new three-drug combination for people with advanced bile duct cancer that has a specific marker called HER2. The goal is to see if the combination can shrink tumors and control the disease. About 65 participants will receive the treatment, and researchers …

This study aims to find out which procedure works better for people with long-term blockages in their leg arteries. Researchers will compare using a special drug-coated balloon alone versus using that balloon after first removing some of the artery-clogging plaque. The goal is to…

This study aims to check if a drug called rituximab is safe for children with Duchenne muscular dystrophy (DMD) who can still walk. It will involve 5 boys aged 6-10 and follow them for one year, closely watching for any side effects. The researchers will also measure changes in t…

This study is for people with type 2 diabetes who are at high risk of breaking a bone due to osteoporosis. Researchers want to see if a drug called denosumab, when given with calcium and vitamin D, can make bones stronger and reduce the chance of new fractures. The goal is to fin…

This study is testing if a new drug called SHR-1811, when combined with an existing drug (bevacizumab), can help control advanced colorectal cancer that has spread and worsened after standard first treatment. It will involve about 80 adults whose cancer has a certain level of a p…

This study is testing whether combining two different types of cancer drugs works better than current options for advanced kidney cancer. About 30 patients who haven't had prior treatment will receive both an immunotherapy injection and a targeted therapy pill. Researchers will t…

This study is testing a new type of brain scan to see if it can help doctors better understand and diagnose neurodegenerative diseases like Alzheimer's and Parkinson's. Researchers will give 40 participants a special imaging tracer and use a PET scanner to see how it collects in …

This study aims to see if a new molecular test, called CISENDO, can accurately screen for and track endometrial (uterine) cancer using leftover cells from a routine cervical swab. Researchers will compare the test results to the current standard procedure (a hysteroscopy with bio…

This study aims to create a better system for finding and managing gestational diabetes (GDM) earlier in pregnancy. Researchers will follow 300 pregnant women, using a continuous glucose monitor (CGM) and AI tools to analyze their blood sugar patterns. The goal is to move diagnos…

This study aims to develop and test an artificial intelligence (AI) system to help doctors diagnose five common eye diseases from specialized eye scans called OCT. Researchers will collect scan images and medical information from 2000 patients with conditions like diabetic eye di…

This study is testing a new type of imaging scan for people with multiple myeloma, a blood cancer. The scan uses a special tracer that attaches to a protein found on myeloma cells. Researchers want to see if this new scan can find cancer spots more accurately than the current sta…

This study aims to find people at high risk for developing diabetes much earlier than current tests allow. Researchers will use wearable glucose monitors and artificial intelligence to analyze data from 1,000 healthy adults. The goal is to create a smarter system that can spot wa…

This study is testing whether a new pain medicine called Tegileridine works as well as morphine for teenagers recovering from spinal surgery for scoliosis. Researchers want to see if it provides similar pain relief but with fewer side effects like sleepiness or nausea. The study …

This study is testing if giving the anti-nausea drug ondansetron before an emergency stomach scope can make the procedure easier for patients who are awake. Researchers want to see if it reduces gagging and discomfort, helps the doctor see better, and makes the procedure less str…

This study aims to see if using artificial intelligence to clone the voices of a patient's loved ones can help reduce anxiety and depression in critically ill patients in the Intensive Care Unit (ICU). Nurses will use these familiar, cloned voices when communicating with patients…

This study aims to understand a fast-progressing type of heart artery disease that doesn't respond well to standard treatments. Researchers will compare about 34 patients with this rapid form to about 18 patients with the more common, slower-progressing form. They will look at me…

This study aims to understand how patients with advanced small cell lung cancer respond to standard treatments in everyday hospital practice. Researchers will observe 96 patients receiving their normal care, collecting health data over time to see which approaches work best. The …

This study aims to understand how changes in body fat and muscle affect survival and quality of life in people with obesity-related cancers. Researchers will follow 6,743 newly diagnosed cancer patients across multiple hospitals in China, using advanced imaging to track body comp…

This study aims to understand if the types of bacteria in a patient's gut (the microbiome) influence how well they respond to a lymphoma drug called glofitamab. Researchers will observe 30 patients with a specific type of lymphoma (DLBCL) who are already scheduled to receive this…

This study aims to understand what happens to patients with diffuse large B-cell lymphoma (DLBCL) after their cancer progresses despite treatment with a drug called polatuzumab vedotin. Researchers will look back at medical records and follow patients forward to see what treatmen…

This study aims to create a detailed map showing where colon cancer spreads to lymph nodes in a specific area of the gut. Researchers will examine tissue from 406 patients undergoing surgery for right-sided colon cancer. The goal is to provide surgeons with better evidence on how…