POSTOPERATIVE PAIN

This study tests two ways to numb the area for collarbone fracture surgery. One method (SCB-ISB) is standard but can sometimes cause breathing problems. The other (SCB-CPB) aims to provide the same pain relief with fewer breathing risks. 34 adults having collarbone surgery will b…

This study looks at whether showing children a video before their tonsil surgery can lower their fear, anxiety, and pain. About 60 kids aged 4 to 10 will watch a video that explains the surgery in a child-friendly way. Researchers will then measure their emotions and pain using s…

This study looks at whether people recovering from inguinal hernia repair can manage pain without opioids. About 900 adults having routine hernia surgery will either receive no opioids or a small supply (5 pills) after their operation. The goal is to see if skipping opioids leads…

This study aimed to see if injecting a long-acting painkiller called Exparel into the vaginal cuff before a minimally invasive hysterectomy could reduce pain after surgery. It was designed for adults having robotic or laparoscopic hysterectomy for non-cancer reasons. However, the…

This study looked at whether giving a long-acting steroid just before removing impacted wisdom teeth can lessen pain, facial swelling, and trouble opening the mouth afterward. Sixty adults aged 18 to 35 took part, receiving either the steroid or a placebo. The goal was to see if …

This study will follow 300 adults who are having plastic surgery and receiving standard light therapy with a device called ELIXIR MD. Researchers want to see how pain, swelling, and bruising change over time, and how satisfied patients are with their recovery. Participants will a…

This study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. 90 adults aged 20-60 participated. Researchers measured anxiety levels before surgery and pain up to 24 hours after, along with vital …

This study compares two types of nerve blocks (M-TAPA and RSB) to see which works better for pain after abdominal surgery. Sixty adults having surgery through a midline belly cut will be enrolled. The goal is to find which method reduces pain and the need for extra pain medicine.

This study compares two types of ultrasound-guided pain blocks (TAP block and quadratus lumborum block) in 70 adults undergoing open inguinal hernia repair with spinal anesthesia. The goal is to see which block better reduces pain and the need for opioid painkillers after surgery…

This study looks at whether giving extra numbing medicine during nose surgery can help patients use fewer strong pain pills afterward. About 50 adults having nose surgery will be randomly assigned to receive either the extra numbing medicine or not. The goal is to see if this app…

This study looks at whether a special nerve block (quadro-iliac plane block) can reduce pain and the need for painkillers after kidney stone surgery. About 60 adults having this surgery will be included. The goal is to see if this block makes recovery more comfortable and lowers …

This study planned to compare a less invasive version of open hemorrhoid surgery with the standard approach in adults with grade III hemorrhoids. The goal was to see if the gentler method causes less pain after surgery. However, the trial was withdrawn before any participants wer…

This study looks at whether a dexamethasone injection can reduce pain after removing impacted wisdom teeth. 70 adults will be split into two groups: one gets standard numbing, the other gets an extra steroid shot. Pain levels are measured using a simple 0-to-10 scale at 24, 48, a…

This study looks at two ways to manage pain after gynecological surgery: the EXORA block and epidural analgesia. Researchers want to see which method helps patients recover better and feel less pain. About 60 adults having elective gynecologic surgery will take part, and their re…

This study compares two types of nerve blocks (serratus plane block and rhomboid intercostal plane block) to see which provides better pain relief after breast reduction surgery. 90 women will receive one of the blocks before surgery, and their pain levels and need for opioid pai…

This study tests whether adding a second medicine (dexmedetomidine) to the standard nerve block medicine (dexamethasone) can make pain relief last longer after shoulder, foot, or ankle surgery. About 100 adults will receive either the combo or the standard block, then report thei…

This study tests a recovery plan called ERAS in 60 adults getting a kidney from a live donor. The plan includes a pre-surgery drink, Tylenol, gabapentin, numbing medicine during surgery, and early walking. Researchers want to see if it lowers pain and the need for strong painkill…

This study looks at whether a special nerve block (called ESPB) can help control pain after surgery for a slipped disc in the lower back. The goal is to see if it reduces the need for strong painkillers, helps people get up and move sooner, and shortens their hospital stay. The s…

This study tests whether an ultrasound-guided nerve block (superficial cervical plexus block) can reduce pain after neck surgery. Sixty adults having elective neck surgery under general anesthesia will receive the block, and their pain levels and opioid use will be tracked for 24…

This study tests whether a special nerve block (erector spinae plane block) can lower the need for strong painkillers after open abdominal surgery. About 46 adults having abdominal surgery under general anesthesia will be randomly assigned to receive the block or not. The main go…

This study looks at two types of nerve blocks—pericapsular nerve block and anterior quadratus lumborum block—to see which one better reduces pain in people having surgery for a broken hip. The goal is to make the spinal anesthesia process less painful and improve pain control aft…

This study compares two types of nerve blocks for pain after arthroscopic shoulder surgery. One block targets the shoulder directly, while the other aims to avoid temporary paralysis of the diaphragm, which can affect breathing. Thirty adults having shoulder surgery will be rando…

This study compares two types of nerve blocks (quadratus lumborum block and retrolaminar block) to see which one better controls pain after lumbar disc surgery. Researchers will measure pain scores, opioid use, and patient satisfaction in 84 adults. The goal is to find a more eff…

This study tests if a nerve block (serratus intercostal plane block) works better than the usual numbing medicine injected at the surgical cuts (port infiltration) for pain after gallbladder removal. 128 adults having laparoscopic gallbladder surgery will be randomly assigned to …

This study looks at whether adding flurbiprofen axetil to a standard scalp numbing medicine can better control pain after brain surgery. About 216 adults having brain surgery will receive either the numbing medicine alone or with flurbiprofen. The goal is to see if the combinatio…

This study looks at whether a special nerve block (serratus posterior superior intercostal plane block) can reduce pain and the need for painkillers after cervical disc herniation surgery. About 40 adults having this neck surgery will be included. The goal is to see if this block…

This study compares two types of nerve blocks (S-TAP vs. Rectus Sheath Block) to see which one better controls pain after abdominal surgery with a midline cut. Sixty adults having this surgery will rate their pain and track how much extra pain medicine they need. The goal is to f…

This study aimed to see if taking oral steroids (methylprednisolone) after rhinoplasty (nose job) reduces pain, nausea, swelling, and bruising. It planned to enroll adults having their first nose surgery, but was withdrawn before any participants joined. The goal was to improve p…

This study looks at how children's genes affect their response to pain and opioid medications after surgery. Researchers will analyze DNA from 1,200 children aged 3-15 undergoing tonsillectomy to find genetic markers linked to pain sensitivity and morphine side effects. The goal …

This study looks at how increasing doses of the opioid remifentanil change a person's pain threshold just before anesthesia. About 40 adults scheduled for surgery will have their pain threshold measured with a pressure device at different drug levels. The goal is to better unders…

This study looks at whether certain blood markers of inflammation can predict how well dental numbing works and how much pain people feel after treatment. Researchers will check blood samples and anesthesia success in 150 adults with tooth pain. The goal is to help dentists bette…

This study looks at 68 knee replacement patients to see if the exact spot where a nerve block is injected changes how well it works. Doctors will compare two injection levels and measure how far the numbing medicine spreads, pain scores, and any side effects like falls. The goal …