Numbing injection may slash opioid pills needed after rhinoplasty
NCT ID NCT06989866
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 36 times
Summary
This study tests whether a numbing injection (bupivacaine) given after nose surgery can reduce the number of strong pain pills patients need. Fifty adults having primary septorhinoplasty will be randomly assigned to receive either the numbing shot or a placebo. Researchers will track how many opioid pills are used and measure pain levels for a week.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Naval Medical Center Portsmouth
Portsmouth, Virginia, 23708, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bupivacaine (a numbing medicine)
What this could lead to
If it works, this could offer a way to manage post-surgery pain with fewer opioid pills, reducing the risk of dependence and side effects.
What could go wrong
This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The numbing effect may not be strong enough to replace opioids for all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.