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Could a Two-Drug nerve block ease Post-Surgery pain?

NCT ID NCT07775053

Symptom relief Sponsor: Sargodha Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 25, 2026 · Updated 3 times

Summary

This trial tests whether adding the painkiller tramadol to a standard local anesthetic nerve block improves pain control after a mastectomy. Women aged 20-70 scheduled for the surgery will receive either ropivacaine alone or ropivacaine plus tramadol in an ultrasound-guided chest nerve block. The study will compare how much pain they feel and how much additional opioid pain medication they need afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A nerve block using the local anesthetic ropivacaine, with or without the painkiller tramadol added.
What this could lead to
If adding tramadol to the nerve block works better, it could offer a more effective way to manage pain after breast cancer surgery and reduce the need for opioid painkillers.
What could go wrong
This is a small, early-stage study, so results may not be definitive. Adding tramadol could also increase side effects like nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 62 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Female Patients aged 20-70 years 2. Patients scheduled for elective unilateral modified radical mastectomy 3. Patients with ASAI andII physical status. Exclusion Criteria: 1. Patients on anticoagulant therapy. 2. Patients with a BMI≥35 kg/m3. 3. Patients with a history of allergy to local anesthetics. 4. Patients with significant neurological or psychiatric disorders. 5. Pregnant patients.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dr Faisal Masood teaching Hospital Sargodha

    Sargodha, Punjab Province, 40100, Pakistan

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