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Wisdom tooth pain? a simple injection might help

NCT ID NCT07538375

Symptom relief Sponsor: 28 Military Dental Centre Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a single injection of dexamethasone, given right after removing an impacted wisdom tooth, can lower pain over the next three days. Seventy adults aged 20 to 40 are taking part at a dental centre in Lahore. Half get the standard numbing shot, and half get an extra dexamethasone injection. Pain is measured using a 0-to-10 scale at 24, 48, and 72 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If it works, this could offer a simple way to ease pain after wisdom tooth removal without extra pills.
What could go wrong
This is a small, single-center trial with 70 people. Results may not apply to everyone, and dexamethasone may not reduce pain better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Dec 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 20 to 40 years * Patients with at least one impacted mandibular third molar (Class A or B, Class I or II) including mesioangular, horizontal, vertical, or distoangular impactions according to Pell and Gregory classification confirmed by panoramic radiograph * Patients with no systemic disease (e.g., diabetes mellitus, hypertension, ischemic heart disease) * Patients of either gender Exclusion Criteria: * Patients who have used analgesics or related drugs within 15 days prior to surgery * Pregnant patients * Patients with known allergy to corticosteroids * Patients with tooth associated with cyst, tumor, or trauma

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative Tooth, Impacted

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted mandibular third molar Postoperative pain

Contacts and locations

Locations

  • 28 Military Dental Centre

    Lahore, Punjab Province, 63000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.