DEXMEDETOMIDINE

This study looked at whether giving a medicine called dexmedetomidine during a procedure to fix a brain aneurysm can help prevent blood vessels in the brain from narrowing (vasospasm). The trial involved 90 adults who had a type of bleeding stroke from a burst aneurysm. Researche…

This study looked at whether adding dexmedetomidine to standard pain relief after cancer surgery helps elderly patients (65-89 years) live longer. Researchers think it might reduce stress and inflammation, improving immune function. 1500 participants were followed for survival an…

This study tested whether adding dexmedetomidine to the standard drug mannitol can better control increased pressure inside the skull during robot-assisted prostate surgery. Sixty adults at low surgical risk took part. The main goal was to measure changes in the optic nerve sheat…

This study tested whether giving a low dose of dexmedetomidine at night can prevent delirium (sudden confusion) in older adults after heart surgery. About 500 patients aged 60-89 were enrolled. The drug aims to improve sleep and reduce brain complications, potentially improving s…

This study tested two medications, dexmedetomidine and lidocaine, given during breast cancer surgery to see which one controls pain better afterward. Forty women having a modified radical mastectomy took part. The goal was to find a way to reduce the need for strong painkillers a…

This study tested three different sedative drugs given as a mist to children aged 3-7 before tonsil surgery. The goal was to see which one helps kids stay calm and separate easily from parents. Sixty children took part, and researchers measured sedation levels and anxiety.

This study looked at whether giving the drug dexmedetomidine during laparoscopic surgery for colorectal cancer helps protect the lungs of patients aged 60 to 84. The researchers measured oxygen levels and breathing function in 64 participants. The goal was to see if this drug can…

This study tested two different doses (5 µg and 10 µg) of the drug dexmedetomidine, added to standard spinal anesthesia, in 60 women having planned C-sections. The goal was to see which dose provides longer pain relief and muscle relaxation after surgery. Researchers measured how…

This study tested three sedation approaches to make removing a Double-J ureteral stent more comfortable. Sixty adults received either propofol alone or propofol combined with dexmedetomidine or midazolam. Researchers measured how much propofol was needed and how sedated patients …

This study tested whether adding dexmedetomidine, a mild sedative, to standard pain relief could lower the risk of delirium (sudden confusion) in older adults after cancer surgery. Delirium is common in elderly patients and can lead to worse recovery. The trial involved 1,500 pat…

This study tested adding dexmedetomidine to a standard numbing medicine for a nerve block after C-section. 80 women received the block after spinal anesthesia. The goal was to see if the combination provides longer pain relief, reduces recovery time, and lowers the need for extra…

This study looked at 60 children aged 3-8 who needed a procedure to close a hole in their heart. Researchers compared full general anesthesia to a lighter sedation with two medicines (dexmedetomidine and ketamine) plus numbing at the catheter site. They measured heart rate and bl…

This study tested whether breathing in a medication called dexmedetomidine before surgery can prevent dangerous spikes in heart rate and blood pressure during weight-loss surgery in people with obesity. 90 adults with a BMI between 30 and 45 took part. The goal was to see if this…

This study tested a new mix of pain medicines (dexmedetomidine, esketamine, and ropivacaine) against the standard mix (sufentanil and ropivacaine) for epidural pain relief during childbirth. 300 pregnant women took part to see if the new combination works as well and is safer for…

This study tested whether giving a combination of two sedative drugs (dexmedetomidine and esketamine) at night can improve sleep quality for adults in the intensive care unit who need a breathing machine or high-flow oxygen. Researchers measured sleep stages using brain monitorin…

This study compared two sedative drugs, remimazolam and dexmedetomidine, to see which better prevents confusion (delirium) after chest surgery in patients aged 60 and older. Delirium is common after surgery and can slow recovery. The goal was to find a safer option with fewer sid…

This study tested two drugs, magnesium sulfate and dexmedetomidine, to see which works better for pain control during bladder tumor surgery. 93 adults having surgery under spinal anesthesia took part. Results showed that magnesium sulfate lowered pain scores, delayed the need for…

This study looked at 78 adults having major spine surgery to compare two anesthesia approaches. One group received propofol, fentanyl, and dexmedetomidine; the other received propofol, fentanyl, and sevoflurane. The goal was to see which combination better preserved nerve signals…

This study looked at how dexmedetomidine, a sedative used during surgery, affects stomach emptying in 80 adults having their gallbladder removed. Researchers used ultrasound to measure stomach volume before and after surgery. The goal was to better understand how this drug might …

This study looked at whether dexmedetomidine, a drug used in general anesthesia, can protect the inner lining of blood vessels (endothelium) from damage during nose surgery. Researchers measured two markers of vessel damage in 90 rhinoplasty patients. The goal was to see if addin…

This study looked at 142 people with hard-to-control high blood pressure who had a procedure to calm overactive kidney nerves. Researchers compared two types of sedation to see which one caused fewer side effects like breathing problems or heart issues. The goal was to find the s…