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Spinal anesthesia boost: which dexmedetomidine dose works best for C-Sections?

NCT ID NCT07395271

Symptom relief Sponsor: Bahria International Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 4 trial tested two different doses (5 mcg vs 10 mcg) of dexmedetomidine added to standard spinal anesthesia for women having planned C-sections. The goal was to see which dose provides longer pain relief and muscle relaxation. Sixty women aged 20-40 participated, and researchers measured how long the anesthesia lasted and monitored heart rate and blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexmedetomidine
What this could lead to
If successful, this could help doctors choose the best dose of dexmedetomidine to improve pain control and recovery after C-section.
What could go wrong
This is a small, completed trial with only 60 participants. Results may not apply to all patients or settings, and side effects like changes in heart rate or blood pressure are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

60 people

The number who actually took part.

Started

Oct 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Parturients aged 20-40 years * ASA physical status II * Scheduled for elective cesarean section * Ability to provide informed written consent Exclusion Criteria: * ASA physical status III or higher * Emergency cesarean section * Previous labor analgesia * History of cardiovascular, neurological, or systemic disease * Contraindications to spinal anesthesia * Surgery duration exceeding 60 minutes

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dexmedetomidine

Contacts and locations

Locations

  • Bahria International Hospital

    Rawalpindi, Punjab Province, 46220, Pakistan

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