New painkiller cocktail could ease C-Section recovery
NCT ID NCT07072650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding dexmedetomidine to a standard local anesthetic (bupivacaine) in a nerve block after C-section can improve pain relief. 80 women having planned C-sections took part. The goal was to see if the combination extends pain-free time, reduces recovery time, and lowers the need for extra pain medication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexmedetomidine
- What this could lead to
- If it works, this could provide longer-lasting pain relief after C-sections with less need for additional painkillers.
- What could go wrong
- This is a small, early-phase trial with only 80 participants. Results may not apply to all patients, and the added drug could cause side effects like sedation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
-
80 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
-
Jun 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 40 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age over 18 years' old and less 40 years. * With body mass indices (BMI) between 18.5 and 34.9 kg/m² * Pregnancy more than 37 weeks with single fetus. * Intact membranes. * Women with a singleton pregnancy. Exclusion Criteria: * ASA class III or higher, * contraindications to spinal anesthesia, * mental or neurological disorders, * chronic heart, renal, or liver diseases, * emergency surgery, * a history of blood coagulation disorders, * allergies or contraindications to the study drugs,
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bint Al-Huda Hospital/ thi qar office directorate
Nasiriyah, Thi Qar, 64001, Iraq
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Other studies related to the condition(s) this trial covers.
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