POSTOPERATIVE ANALGESIA

This study compares two painkillers given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. 174 adults having surgery near the cerebellopontine angle will be randomly assigned to one of t…

This study compares two types of nerve blocks—the PENG block and the Deep Iliacus Plane Block—for pain relief during spinal anesthesia positioning and after hip fracture surgery. 75 adults aged 30-85 will receive one of the blocks plus standard pain medication. The goal is to see…

This study tests whether a specific nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and opioid use after minimally invasive heart bypass surgery. Sixty adults undergoing this surgery will be randomly assigned to receive either the nerv…

This study looks at whether a special ultrasound-guided nerve block (Quadro-Iliac Plane Block) can help control pain after lumbar spinal surgery. Researchers will follow 60 adults who are having elective back surgery and compare those who get the block plus standard pain medicine…

This study compares three different nerve blocks (paravertebral, intertransverse, and erector spinae plane) to see which one works best for pain control after video-assisted lung surgery. Researchers will measure how much opioid pain medicine patients need and their pain scores. …

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will receive either the combo, one drug alone, or…

This study compares two types of ultrasound-guided nerve blocks—TAP block and transversalis fascia plane block—for controlling pain after laparoscopic surgery in children aged 6 months to 16 years. The goal is to see which block provides better pain relief, lasts longer, and redu…

This study compares two types of nerve blocks—PENG block and lumbar erector spinae plane block—to see which one better controls pain after total hip replacement. Fifty-two adults undergoing hip replacement under spinal anesthesia will be randomly assigned to receive one of the tw…

This study compares two types of nerve blocks (ESP block and TAP block) to see which one works better for pain relief after open appendix surgery. About 68 adults having this surgery will be randomly assigned to receive one of the two blocks. The main goal is to see which block r…

This study tests a new medicine called HRS-2129 to see if it can safely reduce pain after abdominal surgery. About 360 adults who are scheduled for abdominal surgery will receive either the new drug or a comparator. The main goal is to measure how much pain relief they feel over …

This study looks at whether a specific nerve block (erector spinae plane block) can help control pain after laparoscopic abdominal surgery. About 50 adults undergoing these surgeries will receive the block, and researchers will measure how long it takes before they need extra pai…

This study looks at whether combining two types of nerve blocks can help people who have heart surgery use fewer strong painkillers (opioids) and recover better. About 90 adults having planned heart surgery will receive one of two nerve block combinations. Researchers will measur…

This study compares two types of ultrasound-guided nerve blocks to control pain after open colorectal surgery. About 50 adults aged 18 to 75 will be randomly assigned to receive one of the two blocks. The goal is to see which method provides better pain relief and reduces the nee…

This study tests if a nerve block (TAP block) is as good as or better than an epidural for pain after major abdominal cancer surgery. About 50 adults having surgeries like stomach, colon, or liver removal will be randomly assigned to one of the two methods. The goal is to see whi…

This study looks at two different methods to control pain after laparoscopic hernia repair. Sixty adults having this surgery will be randomly assigned to receive either a numbing injection into the belly wall or a targeted nerve block guided by ultrasound. The goal is to find whi…

This study tests whether a long-acting numbing medicine (bupivacaine liposome) can provide better pain relief after lung surgery compared to standard numbing medicine. About 496 adults having a lung lobe removed will receive a nerve block before surgery. The goal is to reduce pai…

This study compares two ways to dilute the numbing medicine bupivacaine for a nerve block in the arm. Researchers want to see if using sugar water (5% dextrose) instead of normal saline improves how well the block works and how long pain relief lasts. About 90 adults having arm s…

This study watches 90 adults having open heart surgery to compare three standard pain relief methods: IV drugs, an epidural, or a nerve block. The main goal is to see which method best prevents chronic pain 3 months later. Researchers will also track pain levels, recovery speed, …