Which nerve block wins for hip replacement pain?
NCT ID NCT06821516
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks—PENG block and lumbar erector spinae plane block—to see which one better controls pain after total hip replacement. Fifty-two adults undergoing hip replacement under spinal anesthesia will be randomly assigned to receive one of the two blocks. Researchers will measure pain scores, opioid use, and patient satisfaction over 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (PENG block or lumbar erector spinae plane block)
- What this could lead to
- If it works, this could show which nerve block provides better pain relief after hip replacement, potentially reducing opioid use and improving recovery.
- What could go wrong
- This is a small, early-stage trial with only 52 participants, so results may not apply to everyone. Both blocks are already known to work; the study only compares them, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 52 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Voluntary willingness to participate in the study. * Patients who will undergo Total Hip Arthroplasty surgery. * Patients aged over 18 years. * ASA score I-II-III. * Patients who are fully oriented and can cooperate. Exclusion Criteria: * ASA score IV-V. * Patients who refuse to participate in the study. * Patients under 18 years of age. * Presence of active infection in the area to be operated on. * Chronic pain and continuous analgesic use. * Patients with coagulation disorders. * Patients who cannot cooperate with postoperative pain follow-up. * Patients with allergies to local anesthetic agents. * Presence of neuropathy or myopathy in the operated extremity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Basaksehir Çam Ve Sakura City Hospital
RECRUITINGIstanbul, Türki̇ye, Turkey (Türkiye)
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