New pain drug aims to cut Post-Surgery nausea in brain tumor patients
NCT ID NCT07479446
First seen Mar 19, 2026 · Last updated Jun 23, 2026 · Updated 15 times
Summary
This study compares two painkillers given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. 174 adults having surgery near the cerebellopontine angle will be randomly assigned to one of the two drugs. Researchers will track nausea, pain levels, and other recovery measures for 48 hours after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oliceridine
What this could lead to
If it works, this could offer a painkiller option with less nausea after brain surgery, improving recovery comfort.
What could go wrong
This is an early-phase comparison with a small sample, so results may not apply broadly. Nausea reduction may not be dramatic, and pain control could be similar or worse.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.