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New pain block could make lung surgery recovery easier

NCT ID NCT06165991

Symptom relief Sponsor: Yongtao Sun Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a long-acting numbing medicine (bupivacaine liposome) can provide better pain relief after lung surgery compared to standard numbing medicine. About 496 adults having a lung lobe removed will receive a nerve block before surgery. The goal is to reduce pain and improve recovery quality in the first few days after the operation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 496 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Jan 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\) Age ≥18 years old; 2\) Patients undergoing unilateral initial thoracoscopic lobectomy under general anesthesia (TV or robot-assisted); 3\) American Society of Anesthesiologists (ASA) Grade I - III; 4\) Voluntarily participate in the study and sign the informed consent. Exclusion Criteria: * 1\) Pregnant or lactating women; 2\) Pulmonary wedge-shaped resection; 3\) ≥2 thoracic drainage tubes; 4\) Abnormal liver function: ALT and/or AST\>2×ULN, or TBIL≥1.5×ULN; 5\) Renal function impairment (serum creatinine \>176μmol/L), or received dialysis treatment within 28 days before surgery; 6\) Participate in another research trial involving an investigational drug within 6 months; 7\) A history of drug or alcohol abuse; 8\) Long-term use of opioids (more than 3 months or more than 5 mg daily morphine equivalent per day for 1 month); 9\) History of allergy to local anesthetics or one of the investigational drugs; 10\) Uncontrolled mental or neurological symptoms.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative analgesia Thoracic paravertebral block Thoracoscopic lobectomy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University

    RECRUITING

    Jinan, Shandong, 250014, China

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