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Sedative drug may change stomach emptying during surgery

NCT ID NCT06634524

Knowledge-focused Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether dexmedetomidine, a sedative often used during surgery, changes how quickly the stomach empties in people having their gallbladder removed. Researchers used ultrasound to measure stomach volume in 80 patients before and after surgery. The goal was to see if this drug could affect the risk of stomach contents entering the lungs, a serious complication during anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dexmedetomidine
What this could lead to
If it works, this could help anesthesiologists choose safer drugs to reduce the risk of stomach contents entering the lungs during surgery.
What could go wrong
This is a small, single-center study that only looked at one type of surgery. The results may not apply to other procedures or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Oct 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 21 to 65 years old. * Both sexes. * American Society of Anesthesiologists (ASA) physical status I-II. * Undergoing elective laparoscopic cholecystectomy surgery Exclusion Criteria: * Patient's refusal. * Patients with abnormalities in gastrointestinal tracts (including previous esophageal or gastric surgery, tumors or stricture). * Failure to follow preoperative fasting guidelines. * Patients with a body mass index ≥ 35 * Patients on regular treatment of antacids or prokinetic. * Presence of history of disease causing an increase in the incidence of delayed gastric emptying such as: diabetes mellitus, obesity or electrolyte disturbances. * Pregnancy. * Presence of hepatic or renal dysfunction. * Presence of existing condition causing bradycardia such as heart block, or patients on regular calcium channel blockers or beta blockers.

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Conditions

The condition(s) this trial relates to.

gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dexmedetomidine Gastric emptying Laparoscopic cholecystectomy Ultrasound

Contacts and locations

Locations

  • Tanta University

    Tanta, El-Gharbia, 31527, Egypt

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