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Magnesium sulfate beats dexmedetomidine for Post-Surgery pain relief

NCT ID NCT07445451

Symptom relief Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 93 adults having bladder tumor surgery under spinal anesthesia. It compared two intravenous drugs—magnesium sulfate and dexmedetomidine—to see which better controlled pain after surgery. Magnesium sulfate led to lower pain scores, delayed the need for extra painkillers, and reduced total painkiller use, with no major safety issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

93 people

The number who actually took part.

Started

Dec 2024

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age between 18 and 85 years. Classified as ASA physical status I, II, or III according to the American Society of Anesthesiologists. Patients scheduled for elective transurethral resection of bladder tumor (TUR-M) under spinal anesthesia. Exclusion Criteria: Patients under 18 years or over 85 years of age. Contraindications to spinal anesthesia (e.g., infection at puncture site, coagulopathy). History or current diagnosis of significant cardiac arrhythmia. Known allergy or contraindication to the study drugs (magnesium sulfate or dexmedetomidine). Patients requiring conversion to general anesthesia due to inadequate spinal anesthesia intraoperatively. Mental retardation, cognitive impairment, or communication difficulties that prevent understanding of study procedures or pain assessment. Patients who refuse to participate in the study. \-

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative urinary bladder neoplasm Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bladder tumors Dexmedetomidine Hemodynamic and respiratory monitoring Magnesium sulfate Postoperative pain Spinal anesthesia

Contacts and locations

Locations

  • SBÜ Kartal Dr. Lütfi Kırday City Hospital, İstanbul

    Istanbul, Turkey (Türkiye)

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