Which sedation is safer for kidney nerve procedure? new study investigates
NCT ID NCT07293273
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 142 people with hard-to-treat high blood pressure who had a procedure called renal denervation, which uses energy to calm overactive kidney nerves. Researchers compared two types of sedation—dexmedetomidine versus a fentanyl-propofol combination—to see which one caused fewer side effects during and right after the procedure. The goal was to find the safest and most comfortable sedation approach for this treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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142 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients aged 18 to 80 years who underwent renal sympathetic denervation for resistant essential hypertension. Both male and female patients are eligible. Patients younger than 18 years of age and pregnant women are excluded from the analysis.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-80 years * Underwent renal sympathetic denervation for resistant essential hypertension (2023-2024) * Both male and female Exclusion Criteria: * Age \<18 * Pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kosuyolu Heart Training and Research Hospital
Istanbul, Kartal, 34846, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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