Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Which sedative is safer for elderly surgery patients? new trial investigates

NCT ID NCT07569614

Disease control Sponsor: First Affiliated Hospital of Kunming Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two sedative drugs—remimazolam and dexmedetomidine—to see which one better prevents postoperative delirium (sudden confusion) in patients aged 60 and older after thoracoscopic surgery. A total of 105 participants were randomly assigned to receive one of the two drugs or a placebo. The goal was to find a safer anesthesia option for older adults, who are at higher risk for delirium and related complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Remimazolam tosylate and dexmedetomidine
What this could lead to
If successful, this could point toward a safer sedation option for elderly patients that lowers the risk of postoperative delirium.
What could go wrong
This is a small, completed trial with 105 participants, so results may not apply to all patients. Both drugs have known side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

105 people

The number who actually took part.

Started

Apr 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 60 years; * BMI: 18.5-23.9 kg/m²; * ASA grade II-III; * Preoperative MMSE score ≥ 25; * Signed informed consent before surgery. Exclusion Criteria: * Recent history of sedative, analgesic, or opioid use; * Severe hypertension or significant hepatic or renal insufficiency; * Allergy to the study medications; * Alzheimer's disease or acute phase of mental illness; * History of chronic pain or receipt of analgesic therapy; * Hearing/visual impairment with communication difficulties.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dexmedetomidine are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dexmedetomidine Postoperative delirium (POD) Remimazolam besylate Thoracoscopic surgery

Contacts and locations

Locations

  • First Affiliated Hospital of Kunming Medical University Kunming

    Kunming, Yunnan, 6500000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.