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Could a simple sedative make lung surgery less painful?

NCT ID NCT05863416

First seen Jun 03, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This study tested whether giving the sedative dexmedetomidine during lung surgery (without a breathing tube) can reduce coughing and pain. 144 adults took part. Researchers measured cough severity and the need for other painkillers. The goal is to make recovery smoother and more comfortable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tri-Service General Hospital

    Taipei, 114, Taiwan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexmedetomidine

What this could lead to

If it works, this could offer a way to reduce coughing and pain during lung surgery without needing a breathing tube.

What could go wrong

This is a small, single-center study. The drug may cause side effects like low blood pressure or slow heart rate, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.