BREAST NEOPLASMS

This study tested a daily pill called leflunomide in 17 women with metastatic triple negative breast cancer, a fast-growing type with few treatment options. The goal was to find a safe dose and see if the drug could shrink tumors or slow the disease. Leflunomide is already used f…

This study followed 80 Egyptian women with HER2-positive breast cancer to see how well anti-HER2 drugs like trastuzumab work in real life. The goal was to measure survival and side effects. Researchers compared single-drug versus combination therapy to find the best approach for …

This study tested several immunotherapy-based drug combinations in 144 people with advanced hormone receptor-positive, HER2-negative breast cancer that had worsened after standard treatment. The goal was to see if these combinations could shrink tumors or slow the cancer's growth…

This early-stage study tested a new drug called H3B-6545 in 33 Japanese women with a common type of breast cancer (ER-positive, HER2-negative) that had already been treated with hormone therapy. The main goal was to check the drug's safety and find the right dose. The study did n…

This study tested whether a type of mammogram called angiomammography can predict if breast cancer will fully disappear after chemotherapy. Researchers compared it to MRI in 67 women. The goal is to identify non-responders early so they can switch treatments and improve their cha…

This study tested whether an AI system called Carebot AI MMG can read mammograms as accurately as human radiologists. Researchers used 222 past mammograms from four screening centers and compared the AI's readings to those of three experienced breast radiologists. The goal was to…

This study tested whether a fast breast MRI can detect cancers that mammograms miss in women who had breast-conserving therapy for breast cancer at least three years earlier. About 184 women with a recent negative mammogram and no symptoms received a quick MRI. The goal was to se…

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent chronic pain that sometimes lasts for months after the operation. 260 women having breast-conserving surgery or mastectomy took part. The researchers compared pain leve…

This study tested whether a smartphone app could help breast cancer patients on oral chemotherapy report side effects and stay connected with their healthcare team. 28 patients with metastatic breast cancer took part. The goal was to see if the app could improve monitoring and re…

This study tested a remote monitoring system (CONTINUUM+ CONNECT) in 411 adults with metastatic breast, lung, colorectal, or prostate cancer. Participants used the system at home, with or without nursing support, while others received standard care. The goal was to see if the sys…

This study looked at 80 adults having major breast cancer surgery to see which pain relief method works better: a nerve block (ESPB) or a lidocaine drip. The goal was to find which approach helps patients recover better and feel less pain after surgery. Results will help doctors …

This study compared two radiation techniques for people with early-stage breast cancer after surgery. One method targets only the tumor area (accelerated partial breast irradiation), while the other treats the whole breast. The goal was to see which causes fewer side effects like…

This study looked at how many tissue samples are needed when doing a special type of breast biopsy called contrast-enhanced stereotactic biopsy (CESB). The goal was to find the smallest number of samples that still gives a reliable diagnosis. Researchers studied 77 women with bre…

This study tested whether a 3D ultrasound technique called shear wave elastography can accurately predict how breast tumors respond to chemotherapy before surgery. Researchers measured tumor stiffness at several points during treatment in 140 women with locally advanced breast ca…

This study looked at 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers wanted to see how different surgery and radiation methods affect breast firmness (fibrosis) and how the breast looks afterward. The goal is to help doctors choose treatme…

This study looked at whether social and economic difficulties affect how early breast cancer is found. Researchers compared 684 women with breast cancer, grouping them by their social situation and cancer stage at diagnosis. The goal was to see if those facing hardship are more l…

This study looked at how breast cancer treatments affect sexual health in 25 women who were also considering fertility preservation. Participants filled out anonymous surveys about their sexual function, body image, and emotional well-being before and after chemotherapy. The goal…

This study looked back at medical records of over 500 women in Gulf countries with advanced breast cancer that was previously labeled HER2-negative. Researchers re-tested old tumor samples to find out how many actually have HER2-low breast cancer, a newer subtype. The goal is to …