Nerve block or IV drip: which helps breast cancer patients recover better?
NCT ID NCT06490718
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compared two ways to manage pain after major breast cancer surgery: a nerve block called erector spinae plane block (ESPB) and an intravenous lidocaine drip. 80 adults having breast cancer surgery were randomly assigned to one of the two methods. The goal was to see which approach leads to better recovery quality and less pain after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- erector spinae plane block (ESPB) and intravenous lidocaine infusion
- What this could lead to
- If one method proves better, it could lead to improved pain control and faster recovery after breast cancer surgery.
- What could go wrong
- This is a small, completed trial with only 80 participants, so results may not apply to everyone. Neither method is a cure, and both carry risks like allergic reaction or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ASA I-III patients * 18 to 75 years of age * Patients scheduled for primary breast cancer surgery-mastectomy, modified radical mastectomy and breast conservation surgery with sentinel lymph node biopsy +/- axillary dissection will be included in this study. Exclusion Criteria: * Patient refusal, * Local skin site infection, * Coagulopathy, * History of allergy to local anaesthetics, and * Patients with hepatic, renal and cardiac dysfunction
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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North District Hospital
Sheung Shui, 999077, Hong Kong
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The First Affiliated Hospital
Guangzhou, Guangdong, China
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Other studies related to the condition(s) this trial covers.
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