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Exercise before chemo may shield heart in breast cancer patients

NCT ID NCT03787966

Symptom relief Sponsor: Universidad de Granada Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a tailored exercise program, done either before or during standard breast cancer treatment, could reduce side effects like heart damage and muscle loss. One hundred women with early-stage breast cancer participated. The goal was to see if exercising before treatment starts is more protective than exercising during treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
therapeutic exercise program
What this could lead to
If it works, this could show that doing specific exercises before cancer treatment helps protect the heart and muscles from damage caused by chemotherapy and radiation.
What could go wrong
This is a small, completed study (100 women) that compared two exercise schedules, not a test of a new drug. Results may not apply to all breast cancer patients or other cancers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Sep 2019

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years or older * Breast cancer diagnosis I-III stage * On the waiting list to anticancer medical treatment (at least surgery, chemotherapy and radiotherapy. * If they meet other criteria which predisposes to higher toxicity. * Have signed informed consent. * Have medical clearance for participation. Exclusion Criteria: * Patient underwent previous cancer treatments. * Patients were previously diagnosed with cancer. * Pregnant patients. * Patients performing other type of therapeutic exercise at diagnosis time with an intake \>or = to 150 moderate-intensity or 75 min of vigorous-intensity a day. * Therapeutic exercise practice not recommended because psychiatric or cognitive disorders or cute or chronic condition that prevents exercise (advanced lung disease, oxygen requirement, stenosis \>70%, metastasis etc.).

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Cardiotoxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast neoplasms

Contacts and locations

Locations

  • University of Granada

    Granada, 18016, Spain

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Other studies related to the condition(s) this trial covers.