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Old arthritis drug shows promise against aggressive breast cancer

NCT ID NCT03709446

First seen Mar 19, 2026 · Last updated Jun 13, 2026 · Updated 12 times

Summary

This study tested leflunomide, a pill usually used for arthritis, in 17 women with metastatic triple negative breast cancer (a fast-growing type). The goal was to see if it is safe and can help control the cancer. The drug works by blocking a protein the cancer needs to grow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Mt Sinai Chelesa

    New York, New York, 10011, United States

  • Mt Sinai West

    New York, New York, 10019, United States

Conditions

The condition(s) this trial relates to.

breast disorder breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.