BREAST NEOPLASMS

This study tests a new drug called imlunestrant in 600 premenopausal women with estrogen receptor-positive, HER2-negative breast cancer. Some women will also receive ovarian suppression. The goal is to see how the drug affects cancer cells and the ovaries compared to tamoxifen. T…

This study is a post-marketing surveillance required by Korean regulators to monitor Talzenna's safety and effectiveness in real-world clinical practice. It will enroll 600 patients with advanced breast cancer and a BRCA gene mutation who are already scheduled to receive Talzenna…

This study looks at 40 adults with a common type of advanced breast cancer (HR+/HER2-) that has stopped responding to standard hormone therapy. Researchers want to find the best order to give two targeted drugs (called antibody-drug conjugates) to control the cancer longer and im…

This study aims to see if a less invasive biopsy method, using ultrasound guidance, can accurately detect whether breast cancer has spread to nearby lymph nodes. Researchers will enroll 200 adults with newly diagnosed breast cancer. The goal is to find the best way to identify su…

This study will test if artificial intelligence can create clear breast MRI images without using contrast dye. Researchers will use a special type of MRI scan (diffusion-weighted imaging) to generate synthetic images that might help diagnose breast cancer. If successful, this cou…

This study tests whether a special skin-like sheet (SureDerm) placed during breast-conserving surgery can improve how the breast looks and feels afterward. About 116 women with breast cancer will be randomly assigned to get the implant or standard surgery alone. Researchers will …

This study tests a program called AIMSS-CARE for breast cancer patients who have joint and muscle pain from their hormone therapy. The program includes exercise, education, symptom tracking, and follow-up. Eighty-eight patients in Ethiopia will be randomly assigned to the program…

This study looks at how to best help people who finished early-stage breast cancer treatment get back to their normal activities, like work, socializing, and daily tasks. About 352 participants will try different combinations of three simple tools: identifying priorities, learnin…

This study is testing a new smartphone app designed to help breast cancer patients manage symptoms during chemotherapy. The app asks patients to report their symptoms and then gives personalized advice based on medical guidelines. Nurses can also use the app to make better care d…

This study tests whether listening to positive self-affirmation audio recordings can help reduce pain, depression, anxiety, and stress in women who have had a mastectomy. Forty-two women will be randomly assigned to either listen to the affirmations or receive standard care. The …

This study tests whether a special education program can increase breast and cervical cancer screening among visually impaired women. About 74 women over age 40 will receive training on cancer risks and how to schedule screenings. Researchers will check if screening rates and kno…

This study will send different types of WhatsApp messages to 235,000 people in Chile who are due for cancer or chronic disease screenings. Researchers want to see if the way a message is worded (basic, risk-focused, or peace-of-mind) and whether it mentions one test or both tests…