ACUTE CORONARY SYNDROME

This study tested a new blood thinner pill called milvexian in over 14,000 people who recently had a heart attack or unstable angina. The goal was to see if adding milvexian to standard care could lower the chance of another heart attack, stroke, or death from heart problems. Par…

This study tested two things in over 3,400 people who had a heart attack and needed a stent: whether newer stents that dissolve over time work as well as permanent ones, and whether a lower dose of the blood thinner prasugrel is as safe and effective as the standard dose. The goa…

This study looked at whether sending lifestyle tips and reminders via text message could help people who had a heart attack (acute coronary syndrome) better manage their risk factors and avoid future heart problems. 370 patients took part and received text messages for one year. …

This study tested a hospital care plan that includes a cholesterol-lowering drug called inclisiran for people who recently had a heart attack or unstable angina (acute coronary syndrome). About 400 participants with high LDL cholesterol despite statin therapy were enrolled. The g…

This study tested if evolocumab, a drug that lowers cholesterol, could also reduce inflammation after a heart attack. 100 adults who had a recent heart attack received either evolocumab or a placebo. The main goal was to see how much LDL cholesterol dropped after about a month. R…

This study checked if the Orsiro drug-coated heart stent works safely in everyday patients with blocked arteries. Over 550 people who got the stent were followed for a year. The goal was to see how many had serious heart problems like heart attack or needed another procedure. Res…

This study tested evolocumab, a drug that lowers bad cholesterol, in 60 people who had a specific type of heart attack (NSTEMI). The goal was to see if adding this drug to standard care could reduce cholesterol and inflammation in the heart and blood vessels. Participants receive…

This study looked at a new combination of two blood thinners, rivaroxaban and ticagrelor, in 40 people with atrial fibrillation who had a heart stent placed. The goal was to see if this combo causes less bleeding than the standard three-drug therapy, while still preventing heart …

This study tested whether the anti-inflammatory drug colchicine can reduce common complications after coronary artery bypass grafting in people who recently had a heart attack. One hundred adults were randomly assigned to receive colchicine or a placebo for 30 days after surgery.…

This study tested a decision support system (DSS) that helps doctors pick the best cholesterol-lowering drugs for patients who just had a heart attack. Over 1,100 patients from different hospitals took part. Hospitals either used the DSS or gave standard care. The goal was to see…

This study looked at whether moderate-dose statins can lower bad cholesterol as effectively as high-dose statins in people who recently had a heart attack or unstable angina. 190 adults were randomly assigned to one of two statin strengths and followed for 3 months. The goal was …

This study looked at whether the drug vericiguat helps people who recently had a heart attack or unstable angina and have a weak heart (ejection fraction below 45%). Researchers compared those who took vericiguat regularly to those who did not, tracking deaths, heart failure hosp…

This study looked at whether taking aspirin twice a day (100 mg each time) works better than the usual once-a-day dose to prevent another heart attack, stroke, or urgent heart procedure in people with diabetes who have had a recent heart attack or unstable angina. About 2,500 par…

This study looked at whether doing cardiac rehabilitation at home, or a mix of home and clinic visits, is as effective as going to the clinic for all sessions. 206 adults with heart conditions like heart attack or heart failure took part. The goal was to see if home-based options…

This study tested whether a single daily pill containing a statin, aspirin, and a blood thinner could help underserved heart attack patients who received a stent stick to their medications. 140 adults took either the polypill or their usual separate medicines. The goal was to see…

This study tested a newer type of heart stent (Xience Sierra) in 1757 people with heart disease, including many with diabetes or prediabetes. The goal was to see if the stent is safe and works well in both general and high-risk patients. Researchers tracked heart-related events l…

This study looked at whether taking two blood thinners (clopidogrel and aspirin) for a longer time after getting a heart stent helps prevent future heart attacks, strokes, or death in people with multiple blocked heart arteries. About 8,250 adults aged 18-75 who already had a ste…

This study tested a new method called JINS for placing drug-coated stents in the heart arteries of 161 people with acute coronary syndrome. The goal was to see if this simpler approach could still achieve good stent placement while reducing unnecessary radiation and complications…

This study looked at whether a specific heart ultrasound measurement, called the S' wave, can help emergency doctors quickly identify acute coronary syndrome (a heart attack or unstable angina) in adults with chest pain. Researchers studied 66 patients who came to the emergency r…

This study tested whether offering genetic testing for familial hypercholesterolemia (a genetic condition causing very high cholesterol) to people hospitalized for a heart attack could help doctors diagnose the condition more often. Researchers enrolled 140 patients under age 60 …

This study tested whether a decision rule, which includes a quick blood test for heart damage, can help general practitioners safely decide which patients with chest pain need to go to the hospital. About 946 adults with new chest pain took part. The goal was to reduce unnecessar…

This study looked at whether acupressure, a technique that applies pressure to specific points on the body, can reduce anxiety and improve vital signs like blood pressure and heart rate in people who have had a heart attack (acute coronary syndrome). 68 adults participated. The g…

This study looked at data from nearly 1,800 patients who had a heart attack to find out what causes plaque erosion in the arteries. Researchers combined information from previous studies and new datasets from around the world. The goal is to better understand why plaque erosion h…

This study looked at 88 people with acute coronary syndrome (heart attack or unstable angina) who received contrast dye during a heart procedure. Researchers tracked their kidney function and other factors to find out who is more likely to develop kidney injury from the dye. The …

This study looked at how well two different types of stents (small mesh tubes) heal inside the arteries of people who had a heart attack. Researchers used a special camera to check if the stents were covered by new tissue after 3 months. The goal was to see which stent type might…

This study looked at whether patients who had a heart attack, stroke, or other blood vessel problems were prescribed the right cholesterol-lowering medicine when they left the hospital. The goal was to see how well doctors followed official guidelines. 129 patients were included,…

This study looked at how long people who had a heart attack should take two blood-thinning medicines (aspirin plus a second drug). Over 5,000 patients were randomly assigned to shorter or longer treatment. The goal was to find the best balance between preventing another heart att…

This study aimed to create a personalized risk model for people with acute coronary syndrome (a serious heart condition). Researchers looked at clinical, lab, and genetic data from 1,655 patients to predict the chance of death or other heart problems over two years. The goal was …

This study looked at 2000 patients who had a heart attack or similar event to understand how inherited high cholesterol (familial dyslipidemia) is linked to early heart disease. Researchers reviewed medical records to find patterns in cholesterol problems. The goal was to highlig…

This study looked at how different doses of aspirin affect the body's immune response. Healthy volunteers took various aspirin doses for 10-14 days, then received a substance that causes temporary flu-like symptoms to test their immune reaction. The goal was to see if a lower, tw…

This study tested whether a heart rehab program that mixes video calls, home exercises, and a few clinic visits works for people who survived a heart attack. Only 10 people took part, and the program was cut short due to a technology change. The goal was to see if such a program …

This study looked at how a herbal capsule called Xuesaitong affects blood platelets in people who recently had a heart attack and a stent placed. 60 patients took the capsule for 4 weeks. Researchers analyzed their platelets to understand how the treatment works at the gene, prot…

This study looked at how different blood-thinning drugs are used in Italian hospitals for patients having a heart attack. Researchers tracked over 2,800 patients to see which drug combinations doctors actually use, from arrival to discharge. The goal was to understand real-world …

This study looked at 1,005 people having emergency heart treatment (acute coronary syndrome) who received a stent and were given the blood thinner cangrelor. Researchers tracked how often bleeding occurred within 30 days when patients switched from cangrelor to other common blood…

This study tested a new blood thinner called vicagrel against the standard drug clopidogrel in 18 healthy adults with a specific gene type. The goal was to see how the body processes each drug and how well they work. Participants took both drugs at different times, and researcher…

This study looked at whether a simple blood test, done by paramedics before reaching the hospital, can help identify patients having a heart attack. Researchers combined data from over 5,000 people with chest pain to see how accurate the test is. The goal is to help emergency cre…

This study looked at how a marker of inflammation called C-reactive protein (CRP) changes in the blood of 35 adults having emergency angioplasty for a heart attack. Researchers took blood samples before the procedure and at several time points after, up to 30 days. The goal was t…

This study looked at 1,000 people who had a heart attack to understand why some had no common risk factors like smoking, high blood pressure, or diabetes. Researchers compared those with and without these risk factors to find new clues in blood tests, imaging, and medical history…

This study tested whether giving heart attack patients telemedicine devices to use at home could safely reduce the need for hospital visits. 337 adults with high cardiovascular risk took part after leaving the hospital. Researchers tracked hospital readmissions and emergency visi…