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New model aims to predict heart attack outcomes

NCT ID NCT04068909

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 1,655 people who had a heart attack or unstable angina (acute coronary syndrome) to create a personalized risk model. Researchers used medical tests, genetic information, and other health data to predict who might have worse outcomes or complications from treatment. The goal was to help doctors make better treatment decisions, but the study did not test any new drug or procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,655 people

The number who actually took part.

Started

Nov 2014

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study population consists of consistently hospitalized patients with ACS from 4 vascular centers of Moscow, Kazan, Astrakhan and Krasnodar

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients with acute coronary syndrome without ST-segment elevation meeting the criteria of a very high, high or intermediate risk, and patients from the low-risk group, if they have episodes of myocardial ischemia in any way Very high risk (1 criterion is sufficient) * Pulmonary edema, most probably due to ischemia. * The newly appears or increased noise of mitral regurgitation. * Rhythm of the gallop, newly developed or intensified wheezing in the lungs. * Hypotension against ischemia * Ischemia refractory to treatment * Persistent ventricular tachycardia or the occurrence of ventricular rhythm disturbances during an attack of ischemia High risk (1 criterion is sufficient) * An anginal attack more than 20 minutes within the next 48 hours before admission * Transitional elevations ST (duration less than 20 min) * GRACE score \> 140 points * Increased cardiospecific markers of necrosis. (you must have at least 2 criteria) * Age\> 75 years. * Angina pectoris with transient changes ST\> 0.05 mV. Intermediate risk (1 criterion is sufficient) * Age\> 75 years. * Angina pectoris with transient changes ST\> 0.05 mV. * Inversion of the T wave on ECG (≥ 0.2 mV). * GRACE score 104-139 points (it is necessary to have at least 2 criteria) * Angina of rest (\<20 min), stopped spontaneously or with the help of nitroglycerin (NG). * Anamnesis of pathology of peripheral or cerebral arteries, * Postponed myocardial infarction, including painless, history of revascularization (PCI or CABG) * Diabetes. * Chronic renal failure (GFR \<50 mL / min) Low risk All other patients with suspicion of ACS require a survey to identify episodes of ischemia 2. Patients with acute coronary syndrome with ST-segment elevation Patients who were hospitalized with symptoms due to acute myocardial infarction (the duration of infarction is no more than 10 days, by the time of hospitalization) and at least one of the following additional criteria identified upon admission to hospital: * ST elevation: a persistent ST increase of 1 mm in two adjacent leads from the limbs, or an ST increase of 2 mm in two adjacent thoracic leads * the appearance of a new left bundle branch block * dynamics of acute myocardial infarction 3. Signed informed consent to participate in the study Exclusion Criteria: * Lack of patient consent to participate in the study * Impossibility of contact with the patient after discharge after index event

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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