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Arm cuff trick may shield diabetic kidneys from dye damage

NCT ID NCT07179874

Prevention Sponsor: Universidad de Murcia Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a non-invasive procedure called remote ischemic preconditioning (RIPC) can prevent kidney damage caused by contrast dye in diabetic patients undergoing coronary angiography. The procedure involves using a blood pressure cuff to briefly restrict blood flow to the arm in cycles. Researchers measured kidney function and oxidative stress markers in 71 participants to see if RIPC offers protection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Remote Ischemic Preconditioning (a non-invasive procedure using a blood pressure cuff to briefly restrict arm blood flow)
What this could lead to
If it works, this could offer a simple, drug-free way to protect kidneys in diabetic patients during procedures that use contrast dye.
What could go wrong
This is a small, completed study with only 71 participants, so results may not apply to everyone. Previous research has been mixed on whether this technique works in people with diabetes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

71 people

The number who actually took part.

Started

Feb 2015

Finished

Jan 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient diagnosed with diabetes mellitus. * Age above 18 years. * Admission to the ICU due to acute coronary syndrome. * Indication for undergoing a coronary arteriography (either urgent or scheduled) * Patients who received a coronary arteriography within the last 72 hours (if previously recruited, counted as new for randomization). * Possibility to perform the RIPC maneuver without delaying the catheterization Exclusion Criteria: * Absence of diabetes mellitus. * Pregnant women. * Renal transplant recipients. * Patients who underwent urological procedures or received intravenous contrast within the last 72 hours. * Diagnosis of end-stage renal disease requiring hemodialysis. * Participation in another clinical trial.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome diabetes mellitus acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contrast induced acute kidney injury

More trials for these conditions

Other studies related to the condition(s) this trial covers.