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New blood tests could speed up heart attack detection in emergency rooms

NCT ID NCT00470587

Knowledge-focused Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 10,000 people who came to the emergency room with chest pain. Researchers tested new blood markers to see if they could diagnose heart attacks faster than current methods. The goal is to help doctors quickly rule out or confirm a heart attack, especially in the first few hours when standard tests may not show anything.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to faster and more accurate heart attack diagnosis in emergency rooms, reducing missed cases and unnecessary hospital stays.
What could go wrong
This is an observational study, not a treatment trial. The new markers may not prove better than current tests, and results may not change standard practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

10,000 people

The number who actually took part.

Start date

Apr 2006

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients presenting to the emergency department with typical angina pectoris or other thoracic sensations at rest or minor exertion that are suspected to be caused by myocardial ischemia. Onset of symptoms within the last 12 hours prior to presentation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients presenting to the emergency department * Typical angina pectoris or other thoracic sensations that are suspected to be caused by myocardial ischemia * Symptoms at rest or minor exertion * Onset of symptoms within the last 12 hours prior to presentation * Written informed consent Exclusion Criteria: * Age \< 18 years * Cardiogenic shock * Terminal kidney disease requiring regular dialysis

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome Chest Pain intermediate coronary syndrome myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Angina, unstable Myocardial infarction

Contacts and locations

Locations

  • Emergency Department San Martino Hospital

    Genova, Italy

  • Hospital Clinic of Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico San Carlos

    Madrid, Spain

  • Hospital del Mar

    Barcelona, Spain

  • Kantonsspital Baselland, Standort Bruderholz

    Bottmingen, Switzerland

  • Kantonsspital Baselland, Standort Liestal

    Liestal, Switzerland

  • Kantonsspital Olten

    Olten, Switzerland

  • Klinik St. Anna

    Lucerne, Switzerland

  • Masaryk University Brno

    Brno, Czechia

  • Medical University of Silesia

    Zabrze, Poland

  • Spital Limmattal

    Schlieren, Switzerland

  • University Hospital of Basel

    Basel, 4031, Switzerland

  • Universitätsspital Zürich

    Zurich, Switzerland

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