Heart attack patients: new study reveals hidden kidney danger from routine dye
NCT ID NCT07294911
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study of 88 heart attack patients looked at why some develop kidney injury after receiving contrast dye during a procedure to open blocked arteries. Researchers analyzed medical records to find which factors—like age, lab results, or procedure details—were linked to kidney damage. The goal is to help doctors better predict and prevent this complication in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify which heart patients are at highest risk for kidney injury after contrast dye, leading to better prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks at existing data to find patterns, so it cannot prove cause and effect or directly improve patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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88 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population includes adult patients (≥18 years old) with ST-segment elevation myocardial infarction (STEMI) who underwent emergency percutaneous coronary intervention with intravascular contrast. Participants were prospectively enrolled between November 2024 and June 2025.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age ≥ 18 years Diagnosis of acute coronary syndrome (STEMI or NSTEMI) confirmed by clinical, ECG, and laboratory findings Undergoing coronary angiography or percutaneous coronary intervention with intravascular contrast administration Provided informed consent to participate in the study Availability of baseline and follow-up serum creatinine values Exclusion Criteria: Known chronic kidney disease stage 4 or 5 (eGFR \< 30 mL/min/1.73 m²) or on dialysis Hemodynamic instability not related to acute coronary syndrome (e.g., septic shock) Exposure to intravenous contrast within the previous 7 days Use of nephrotoxic drugs (e.g., aminoglycosides, amphotericin B) within 72 hours prior to contrast exposure Active infection or inflammatory disease affecting renal function Pregnancy or breastfeeding Refusal or inability to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Karaganda Medical University
Karaganda, Qaraghandy Oblysy, 100000, Kazakhstan
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