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Heart attack recovery: could Lower-Dose statins be just as good?

NCT ID NCT06782243

Disease control Sponsor: Khyber Medical University Peshawar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether moderate-dose statins work as well as high-dose statins in lowering 'bad' LDL cholesterol after a heart attack. 190 adults aged 25-85 took either a moderate or high dose of atorvastatin or rosuvastatin daily for 3 months. The goal was to see if both groups could achieve a 50% or greater drop in LDL cholesterol, while also tracking side effects like muscle pain and liver issues.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
statins (atorvastatin and rosuvastatin)
What this could lead to
If moderate-intensity statins work as well as high-intensity ones, doctors may prescribe lower doses to reduce side effects and costs for heart attack patients.
What could go wrong
This is a small, completed trial with only 190 participants. The results may not apply to all patients, and moderate doses might not lower cholesterol enough for some high-risk individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

190 people

The number who actually took part.

Started

Dec 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants aged between 25 and 85 years. * Both males and females. * Diagnosed with acute coronary syndrome as defined in the operational definitions. Exclusion Criteria: * History of adverse reactions to statins (e.g., hypersensitivity, myopathy, acute renal failure). * Current acute liver disease. * Pregnant or breastfeeding women. * Participants already on statin therapy

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute coronary syndrome

Contacts and locations

Locations

  • MTI-KTH (Medical Teaching Institution-Khyber Teaching Hospital), Peshawar-Pakistan

    Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

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