Université De Sherbrooke

This study tests whether group medical visits, where patients meet with a doctor together, can help people with high cholesterol improve their blood fats and lifestyle habits. About 288 adults with dyslipidemia will take part. The goal is to see if this approach makes care more a…

This study tests whether the medication dupilumab can help people with moderate asthma achieve complete control (remission) when given early, before the disease becomes severe. About 150 adults aged 18-79 with moderate asthma and high inflammation markers will receive either dupi…

This study tests whether having a kinesiologist visit older hospital patients more than once a day helps them walk more, become less frail, and go home sooner. About 80 adults aged 50 and older who are expected to stay at least 3 days will take part. Researchers will measure thei…

This study explores whether repeated cold exposure that causes shivering can improve how the body uses insulin in people with type 2 diabetes. Fifteen adults with type 2 diabetes will undergo 10 days of cold acclimation with shivering. Researchers will measure changes in insulin …

This study tests whether taking a low dose of niacin (vitamin B3) after meals can help reduce fat stored in the liver for people with metabolic fatty liver disease (MASLD). Researchers will compare niacin to a placebo in 36 adults aged 50 to 80. The goal is to see if niacin can r…

This study looks at whether the time of day you exercise matters for blood sugar control in people with prediabetes. Researchers will compare morning versus late afternoon exercise in 48 adults with prediabetes. They will measure how the body stores fat and uses energy to see if …

This study is testing a new method called BRAVE that uses sound waves to measure breast tissue stiffness, aiming to find cancer without X-rays or painful compression. Researchers will enroll 300 women who have a breast lump to see how well this technique tells the difference betw…

This study looks at whether two easy, non-invasive tests—a breath test (FeNO) and a blood test (eosinophils)—can accurately diagnose asthma in children aged 6 to 17. Currently, diagnosing asthma often requires a hospital-based breathing challenge test. The goal is to see if these…

This study looks at whether measuring inflammation in the breath and blood can help prioritize who gets asthma testing first. Researchers will include 1,500 people aged 6 and older with suspected asthma. The goal is to see if this approach reduces delays for those most at risk an…

This study tests a procedure called thyroid artery embolization (TAE) for people with large thyroid nodules that cause pressure symptoms like trouble swallowing or breathing. It includes 20 adults who cannot have or choose not to have standard treatments like surgery. The goal is…

This study tests whether dry needling—a treatment using fine needles to release muscle tension—can reduce pain during intercourse in women with provoked vestibulodynia, a common cause of sharp vaginal pain. About 170 women will receive either real or sham dry needling once a week…

This study tests a one-time pain management program called Empowered Relief (ER) against standard care for adults having elective orthopedic surgery. The goal is to see if ER reduces pain intensity and interference at 6 weeks and 3 months after surgery. About 134 French-speaking …

This study tests if wearing a knee brace for the first 3 days after knee replacement surgery can lower pain and help recovery. About 106 adults having a knee replacement will either wear the brace or follow standard care. The goal is to see if this simple approach is worth testin…

This pilot study looks at whether adding a medium-chain triglyceride (MCT) oil supplement to standard antipsychotic treatment can improve metabolism and symptoms in 15 young adults with first-episode psychosis. The supplement provides an alternative energy source for the brain, w…

This study tests whether a daily movement program led by a kinesiologist can reduce frailty in 60 hospitalized heart patients. Frailty makes people weaker and more likely to have longer hospital stays or be readmitted. The program encourages simple activities like standing, walki…

This study tests whether stimulating the tongue with a gentle device can improve arm function and brain plasticity in people who had a stroke at least 6 months ago. 74 participants will receive either real or sham tongue stimulation combined with a personalized 4-week arm trainin…

This study is for first-time mothers having a vaginal birth. It aims to see if the length of time the baby's head is crowning (visible at the vaginal opening) is linked to a tear in a key pelvic muscle. Researchers will use ultrasound after birth to check for muscle injury and as…

This study follows 330 adults with complex kidney cysts (Bosniak III or IV) for 5 years to see if simply monitoring them is as safe as surgery. Many of these cysts are not cancer, and surgery carries serious risks. The goal is to find out whether active surveillance can prevent o…

This study aims to understand why type 2 diabetes often goes away quickly after bariatric surgery. Researchers will track how fat tissue stores dietary fats and how the liver, heart, and muscles use them in 40 people having surgery. Half of the participants have diabetes and half…

This study looks at how lifting light weights versus heavy weights affects blood pressure after exercise in women aged 50-70 who have high blood pressure. Researchers will compare two workout intensities and a control group to see which lowers blood pressure more and why. The goa…

This study is testing several routine treatments used in intensive care units (ICUs), such as medications for low blood pressure, platelet transfusions, and nutrition plans. It will include about 5,500 critically ill patients across multiple hospitals. The goal is to find out whi…

This study trains medical students by having them interview 6000 Quebec adults about their health, lifestyle, and access to care. Participants must have had COVID-19 between November 2020 and May 2021. The goal is to better understand public health issues and help plan health ser…

This study aims to learn about the reproductive health experiences of female members and veterans of the Canadian Armed Forces. Researchers will survey over 1,000 women and interview many more to understand issues like contraception, pregnancy, infertility, and pelvic floor probl…

This study looks at whether teaching science outside for 5 weeks helps 5th and 6th graders learn better, feel more connected to nature, and have less worry about the environment (eco-anxiety). About 1000 children from schools in Montreal, Longueuil, and Laval will take part. Half…

This study looks at how people with lipoprotein lipase deficiency (LPLD) handle dietary fat. LPLD causes very high blood fat levels, leading to belly pain and risk of pancreatitis. Researchers will use special imaging and breath tests to see how fat is stored and used by the hear…

This study looks at how a 2-hour bout of sitting affects blood pressure over the next 24 hours in healthy adults aged 18-65. Researchers will measure artery function and blood pressure before, during, and after sitting, and test whether blocking certain artery-relaxing chemicals …