Ruijin Hospital

This study will test whether a new drug called firsekibart works better than an existing treatment (anakinra) for controlling Adult-Onset Still's Disease. Researchers will enroll 20 adults with active disease to see which treatment more effectively reduces symptoms like fever and…

This study is testing whether using a bedside ultrasound machine to guide suctioning of breathing tubes can make the procedure safer and more effective for ICU patients on ventilators. Researchers will compare the standard method to the ultrasound-guided method in over 300 patien…

This study is testing whether adding an experimental immunotherapy drug called IBI363 to standard chemotherapy helps people with advanced pancreatic cancer that has worsened after initial treatment. About 48 patients whose cancer has spread or cannot be surgically removed will re…

This study is testing if adding an immunotherapy drug called QL1706 to standard chemotherapy can help shrink tumors in people with a hard-to-treat form of esophageal cancer. The goal is to make surgery more successful. About 24 participants in China will receive the drug combinat…

This is an early safety study testing a new drug called GB261 in people with systemic sclerosis, a condition that causes skin and organ hardening. The study will enroll 10 adults who have had the disease for 7 years or less and haven't responded well to other treatments. Research…

This study is testing whether combining two powerful treatments—CAR-T cell therapy and a drug called glofitamab—is safe and effective for people with high-risk, relapsed, or hard-to-treat large B-cell lymphoma. It will enroll about 24 participants at a single hospital in China. T…

This study is testing whether adding an experimental drug called golidocitinib to a standard chemotherapy regimen (GemOx) is safe and effective for adults with peripheral T-cell lymphoma that has returned or not responded to at least one prior treatment. The goal is to see if thi…

This study is testing the safety and effectiveness of an experimental oral medication called gimacabtinib for patients with severe acute graft-versus-host disease (GVHD). It is for adults who have had a stem cell transplant and whose GVHD did not improve or got worse after trying…

This early-stage study is testing a new, personalized mRNA vaccine (XP-006) for safety and early signs of effectiveness. It is for adults with B-cell non-Hodgkin's lymphoma that has returned or not responded to prior treatments. The vaccine is designed to teach the patient's own …

This study is testing whether adding the drug zanubrutinib to standard chemotherapy helps control a rare and aggressive type of brain cancer called primary central nervous system lymphoma. It will enroll 19 newly diagnosed patients in China to see if this combination leads to com…

This is a very early study to check if a new drug called cizutamig is safe and how it behaves in the body of people with systemic sclerosis. It will involve 10 adults with a specific, more severe form of the disease who haven't responded well to other treatments. The main goal is…

This study is testing if a new pill called Onradivir can help teenagers with the flu get better faster. About 150 teens aged 12-17 with confirmed flu A will take either the real pill or a placebo for 5 days. Researchers will track how quickly their symptoms go away and how much f…

This study is testing whether a combination of three targeted drugs (tazemetostat, linperlisib, and golidocitinib) can help control a rare and aggressive blood cancer called peripheral T-cell lymphoma in patients whose disease has returned or not responded to prior treatment. The…

This early study aims to check if a new drug called cizutamig is safe and how it affects the immune system in people with moderate to severe ulcerative colitis. It will include 15 adults whose current treatments aren't working well enough. Researchers will monitor participants cl…

This study is testing whether adding a new drug called BEBT-908 to standard chemotherapy can help patients with a specific type of acute lymphoblastic leukemia. It focuses on adults who are in remission but still have tiny amounts of cancer cells detectable in their body. The goa…

This study is testing whether adding a new immunotherapy drug (SHR-1701) to standard chemotherapy works better for advanced stomach cancer that has spread to the abdominal lining. Researchers will compare two different drug combinations in 60 patients who haven't had prior cancer…

This study aims to find out which of two special hypoallergenic baby formulas works better for relieving symptoms while doctors try to diagnose a cow's milk protein allergy. It will involve about 360 babies under 6 months old who are suspected of having this allergy. Babies will …

This study is testing a new AI software that helps a robotic bronchoscopy system automatically and accurately map the lungs. It will involve 20 patients who need a procedure to locate a lung nodule before surgery. The main goal is to see if the AI can successfully guide the robot…

This study aims to see if a camera system using artificial intelligence (AI) can predict delirium, a serious state of confusion, in intensive care unit (ICU) patients. The system will analyze patients' subtle facial expressions and movements without touching them. Researchers wil…

This study is testing whether a special, easier-to-digest baby formula can help reduce mild allergy symptoms in infants. It will compare this formula to a regular one in about 160 babies who are mostly formula-fed and have mild skin or tummy troubles. The main goal is to see if t…

This study is testing whether electrical stimulation of the spinal cord can help people with Parkinson's disease and related disorders who experience a dangerous drop in blood pressure when they stand up. It will compare two types of stimulation—one that requires surgery and one …

This study aims to collect detailed information from 1000 people with lymphoma to understand how different treatments work in real-world settings. Researchers will track patients' treatment plans, disease characteristics, and long-term health outcomes. The goal is to use this inf…

This study aims to find patterns in the blood and lung fluid of 411 adults with severe lung failure (ARDS) who are on breathing machines. Researchers will analyze tiny organisms, chemicals, and genes to see which patterns are linked to how patients respond to the ventilator and w…