New combo therapy aims to beat tough lymphoma

NCT ID NCT07326371

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining two powerful treatments—glofitamab and CAR-T therapy—can help people with a high-risk, hard-to-treat type of large B-cell lymphoma that has come back or not responded to prior treatment. About 24 adults will receive the combination and be monitored for tumor shrinkage and side effects. The goal is to see if this approach improves response rates and disease control.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma high grade B-cell lymphoma interdigitating dendritic cell sarcoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.