Ruijin Hospital

This early study tested a single injection of HM2002, a circular RNA, given directly into the heart muscle during bypass surgery. Only 3 people with heart failure took part. The main goal was to check safety, not to prove it works. The study is complete, but results are not yet a…

This phase 2 trial tested a combination of chemotherapy drugs given directly into the liver artery for people with pancreatic cancer that had spread only to the liver and stopped responding to standard treatment. The 40 participants received a mix of oxaliplatin, irinotecan lipos…

This study looked back at 275 pemphigus patients to see how different doses of rituximab affected disease control and relapse. Pemphigus is a rare autoimmune disease that causes painful blisters on skin and mucous membranes. Researchers tracked outcomes like flare-ups, side effec…

This phase 2 trial tested whether the drug telitacicept can reduce levels of harmful antibodies in 20 people with antiphospholipid syndrome, a condition that raises the risk of blood clots. Participants received either telitacicept plus standard care or standard care alone for 48…

This study compared robotic-assisted pancreatic surgery to the standard open approach for people with pancreatic and related tumors. Researchers wanted to see if robotic surgery could help patients recover faster after the operation. A total of 268 patients took part across multi…

This study tested two different brain areas for deep brain stimulation (like a pacemaker for the brain) in 27 people with tremor-dominant Parkinson's disease. The goal was to see which target—the posterior subthalamic area or the subthalamic nucleus—better reduces shaking. Each p…

This study looked at 332 people with low-risk papillary thyroid cancer that had spread to neck lymph nodes. Researchers compared robotic surgery (done through small cuts in the armpit and breast) with traditional open surgery. They wanted to see if the robotic method removes canc…

This pilot study tested a special microscope-like camera (endocytoscopy) to diagnose upper gut graft-versus-host disease (aGVHD) in 14 patients who had a stem cell transplant. The camera was used during a standard endoscopy to see cells in real time. The goal was to see if this t…

This study tests a new method to measure lung blood flow using electrical impedance tomography (EIT) without requiring patients to hold their breath. Twenty-four adults on respiratory support will receive a salt-water injection and have their lungs scanned during normal breathing…

This completed study tested a new radioactive tracer called [18F] - FD17 for PET imaging to detect clumps of a protein called alpha-synuclein in the brain. These clumps are linked to Parkinson's disease, multiple system atrophy, and a sleep disorder that often precedes Parkinson'…

This study tested whether combining repetitive transcranial magnetic stimulation (rTMS) with motor training helps stroke patients regain arm function. 60 participants were split into three groups: online rTMS during training, offline rTMS before training, or sham stimulation. The…

This study aimed to predict whether high-flow nasal oxygen therapy would fail within 30 minutes for patients with acute respiratory failure. Researchers used data from 164 participants, including a special imaging technique called electrical impedance tomography, to build a predi…

This study created a new tool called the SAH Index to fairly evaluate how well hospitals and surgeons perform gastric cancer surgery. Gastric cancer is serious and often requires major surgery, but comparing results is tricky because patients have different health risks. The rese…

This study tested whether a special imaging method called electrical impedance tomography (EIT) can help doctors choose the best ventilator settings for patients with severe lung injury (ARDS). The goal was to see if EIT could identify which patients would benefit from higher or …

This study tested a new way to predict if patients on breathing machines can safely have the tube removed. Researchers used a special imaging technique called electrical impedance tomography (EIT) to measure how well the lungs fill with air during a breathing trial. The goal was …

This study looked at 375 people having lung nodule surgery. It compared using one breathing tube throughout the procedure versus switching to a different tube partway through. The goal was to see if the simpler method is just as safe and effective, with fewer complications like p…