Heart bypass drug showdown: which pill keeps arteries open longest?
NCT ID NCT04310995
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares three common heart medications (nicorandil, diltiazem, and isosorbide mononitrate) to see which best prevents the narrowing or failure of radial artery grafts used in coronary artery bypass surgery. About 150 adults who recently had bypass surgery will take one of the three drugs for 24 weeks, with follow-up imaging and check-ups at 1 week, 24 weeks, and again after 5 years. The goal is to find the most effective anti-spasm treatment to keep grafts open and reduce future heart problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, 200025, China