Can brain scans predict the progression of silent stroke damage?

NCT ID NCT07726654

Not yet recruiting Knowledge-focused Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This observational study follows 400 adults with cerebral small vessel disease (CSVD) to understand how the condition progresses over time. Participants undergo annual brain scans (MRI and PET), cognitive tests, and blood work to track changes in brain structure, blood flow, and memory. The goal is to identify early markers of disease worsening, which could eventually help doctors intervene sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal early biomarkers and patterns of brain damage in cerebral small vessel disease, guiding future treatments.
What could go wrong: As an observational study, it does not test any treatment. Results may not lead directly to therapies, and findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cerebral Small Vessel Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL SMALL VESSEL DISEASE

Contacts and locations

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Locations

Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, 200025, China

Contact

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

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