Promising combo tackles tough lymphoma

NCT ID NCT07279584

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests a combination of the drug golidocitinib plus chemotherapy (gemcitabine and oxaliplatin) in 31 adults with relapsed or refractory peripheral T-cell lymphoma, a rare and aggressive blood cancer. The goal is to see if the combo safely shrinks tumors and delays disease worsening. Participants must have had at least one prior treatment and have measurable tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
golidocitinib combined with gemcitabine and oxaliplatin
What this could lead to
If successful, this combination could offer a new treatment option for people with relapsed or refractory peripheral T-cell lymphoma, potentially improving tumor shrinkage and delaying disease progression.
What could go wrong
This is a small, early-phase trial with only 31 participants, so results may not apply to all patients. The combination may cause side effects like low blood counts or nerve damage, and it is not yet known if it works better than existing therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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