Peking University Third Hospital

This study compares three different schedules of shock wave therapy for people with partial rotator cuff tears, a common cause of shoulder pain and limited movement. The goal is to see if a high-frequency, short-course treatment (daily sessions for one week) works as well as or b…

This study tests whether Zishen Yutai Pill, a traditional Chinese herbal medicine, can improve live birth rates in women who have had repeated failure to implant embryos after IVF. About 878 women aged 20-40 will receive either the pill or a placebo before and after frozen embryo…

This early study tests a personalized vaccine (YS247) made from a patient's own immune cells to fight a specific type of ovarian cancer (HRD-negative). Only 9 women who haven't been cured by standard therapy will take part. The main goal is to check safety, not yet to prove it wo…

This study tests a comprehensive health management platform for people with early-stage Cardiovascular-Kidney-Metabolic (CKM) syndrome. The platform includes health screening, personalized diet and exercise plans, and regular follow-up. Researchers will enroll 150 participants to…

This study tests whether giving two drugs (toripalimab and 9MW2821) before surgery can improve outcomes for people with localized upper tract urothelial carcinoma, a type of cancer in the kidney or ureter. About 40 adults will be randomly assigned to either the drug combo followe…

This study is testing a new zirconia ceramic hip joint prosthesis in 290 people who need a first-time total hip replacement. The goal is to see if the implant is safe and works well over one year. Participants will be followed for 12 months after surgery to track their recovery a…

This phase 2 trial tests two oral drugs, zeprumetostat and fuzuloparib, in 30 people with advanced or recurrent ovarian cancer who do not have BRCA gene mutations. The goal is to see if the combination can shrink tumors and delay progression. Participants first take fuzuloparib a…

This early-phase trial will test BCT301, a type of immune cell made from stem cells, in 10 people with severe autoimmune diseases like lupus and scleroderma. Participants receive a single infusion of these cells after a short course of chemotherapy. The main goal is to check safe…

This study tests whether injecting a woman's own platelet-rich plasma (PRP) into her ovaries can help improve egg production and IVF success. It includes 142 women with poor ovarian response or premature ovarian insufficiency. The treatment is given via ultrasound-guided injectio…

This study tests a new treatment for women whose ovaries don't respond well to fertility drugs, making it hard to get eggs for IVF. Doctors will take cells from the patient's own fat or blood and inject them into the ovaries. The goal is to see if this improves egg count and preg…

This trial tests whether Mailuo Shutong Pills, a Chinese herbal medicine, can help heal diabetic wounds in people with a specific traditional Chinese medicine pattern (damp-heat toxin accumulation). About 56 adults with diabetes and a wound between 1 and 40 cm² will be randomly a…

This study tests a new way to detect early damage in the feet of people with diabetes by measuring how the skin responds to pressure. Researchers will compare 200 people with and without diabetes to see if skin stiffness and stretchiness can predict ulcer risk. The goal is to pre…

This study tests a new wireless pressure microcatheter to diagnose coronary microvascular dysfunction (CMD) in people with chest pain but no major artery blockages. Researchers will compare the device's measurements to heart MRI scans in 114 participants. If accurate, it could of…

This study tests a new, non-invasive wearable device that uses electrical impedance tomography to monitor bladder function in 40 men with benign prostatic hyperplasia (BPH). Participants will wear the device while undergoing standard urine flow tests to see if the new method matc…

This study tests whether a 12-week program of diet changes, supplements, exercise, and better sleep can improve fertility scores in women aged 20-40 who show early signs of fertility decline. Researchers will enroll 384 women across six medical centers in China, using the OvaRePr…

This study tests whether a specific mix of probiotics can prevent allergies in breastfed infants who received antibiotics within their first month of life. Researchers will give the probiotic or a placebo to 400 babies and track allergy development, gut bacteria changes, and grow…

This study tests whether an AI-based digital rehabilitation system can help people with shoulder impingement syndrome. 93 adults will either do traditional in-clinic therapy plus home exercises, or use the 'ShuKangShi' AI system at home for daily training. The goal is to see if t…

This study tests a new digital system that uses wearable sensors, cameras, and AI to guide people through knee rehab exercises at home. It focuses on two common knee problems: ACL tears and patellar pain. 160 adults aged 18-50 will do strength, balance, and stretching exercises f…

This study looks at whether losing weight can make psoriasis treatments more effective in overweight or obese patients. About 70 adults with moderate-to-severe plaque psoriasis will either get standard care alone or standard care plus a personalized weight loss plan (diet, exerci…

This study compares two ways to give steroid medicine to people with chronic sinusitis who have lost their sense of smell due to blocked nasal passages. One group will get standard steroid spray, while the other gets steroid drops placed directly where smell happens. The goal is …

This study tests whether adding steroid nasal drops to standard smell training can improve smell function in people who lost their sense of smell after an infection (like a cold or COVID-19). 100 adults with impaired smell will receive either steroid drops plus training or placeb…

This study looks at whether using a pillow placed behind the shoulder after rotator cuff repair surgery can lower pain and improve sleep. About 126 adults aged 40 to 70 will choose whether to use the pillow or not. Their pain, sleep quality, and shoulder function will be checked …

This study tests whether doing virtual reality (VR) brain exercises for a few days before surgery can help older adults with cerebral small vessel disease avoid confusion or memory problems after their operation. Two hundred forty participants will either receive VR training or s…

This study tests whether a traditional Chinese medicine hand-foot soak can reduce nerve pain and skin reactions caused by chemotherapy. About 300 adults with solid tumors who have these side effects will use the soak. The goal is to see if it improves symptoms and quality of life…

This study tests whether adding single-leg 20-degree squats to standard physical therapy helps people walk better after anterior cruciate ligament (ACL) reconstruction. The trial will enroll 48 adults aged 18-45 who have ACL surgery scheduled. Researchers will measure knee moveme…

This study tests whether an artificial intelligence system can create personalized exercise plans for people with rheumatoid arthritis. 147 patients with mild-to-moderate disease will be split into three groups: one using the AI system via a smartphone app, one using paper exerci…

This study compares a modern silver foam dressing to a traditional dry silver dressing for chronic wound infections. Researchers will track how much the wound shrinks in two weeks and how many wounds fully heal. The goal is to find which dressing works better and costs less for p…

This study tests whether specific foot exercises—like toe yoga and arch doming—can improve big toe movement and walking patterns in people with chronic plantar fasciitis. Researchers will measure pain, foot function, and gait in 34 adults aged 25-45. The goal is to see if these s…

This study aims to create an AI-based warning system that helps people with diabetes detect early signs of foot ulcers returning. Researchers will follow 200 adults with healed diabetic foot ulcers, using a home monitoring tool and personalized follow-up plans. The goal is to cat…

This study looks at two ways to help people with Charcot-Marie-Tooth disease (CMT) walk better. One group gets foot surgery followed by rehabilitation, the other gets only physical therapy. Researchers will track walking speed and endurance for up to two years to see which approa…

This study will test a new way to score CT scans to see how well it measures smell loss in people with central compartment atopic disease (CCAD), a type of nasal allergy. Researchers will compare the new scoring system to the traditional one in 120 participants. The goal is to im…

This study focuses on extremely preterm infants (born before 32 weeks) who have a heart condition called hsPDA. Researchers will collect blood samples and health data to create a model that predicts which infants need treatment. They are also developing a targeted drug-delivery s…

This study aims to build an AI-powered early warning system to detect signs of diabetic foot ulcer recurrence before it happens. Researchers will follow 200 people whose foot ulcers have healed, using smart tools to monitor risk factors at home. The goal is to create personalized…