Peking University Third Hospital

This study will test a new zirconia ceramic hip joint in 290 people who need a hip replacement. The goal is to see if the joint is safe and works well. Participants will be followed for one year after surgery to check their recovery and joint function.

This study tests whether combining two drugs, zeprumetostat and fuzuloparib, can shrink tumors in people with advanced or recurrent ovarian cancer. About 30 adults aged 18-75 with a specific genetic profile (BRCA1/2 wild-type) will take part. The main goal is to see how many pati…

This early-phase study tests a new treatment called BCT301 for people with severe autoimmune diseases like lupus and scleroderma that haven't responded to standard therapies. BCT301 uses immune cells made from stem cells to target and attack faulty immune cells. The main goal is …

This study tests whether giving a TNF-alpha blocker within 6 hours of restarting the heart can improve survival and brain recovery in patients who remain unconscious after cardiac arrest. The drug aims to calm the body's harmful inflammatory response. About 208 adults with suspec…

This study tests whether Mailuo Shutong Pills, a Chinese herbal medicine, can help heal diabetic wounds faster when added to standard care. About 56 adults with diabetes and a specific type of wound will take the pills or a placebo for 14 days. The goal is to see if the pills red…

This early study tests a personalized treatment for a specific type of ovarian cancer (HRD-negative) that hasn't responded well to standard therapy. The treatment uses the patient's own immune cells, trained to recognize their tumor's unique markers, to try to control the disease…

This study tests whether giving two drugs (toripalimab and 9MW2821) before surgery can improve outcomes for people with a rare cancer of the upper urinary tract. About 40 adults with localized disease will be randomly assigned to either the drug combo followed by surgery, or surg…

This study tests a new treatment for women with poor ovarian response, a condition where the ovaries don't produce enough eggs for IVF. Doctors will inject the patient's own cells (from fat or blood) into the ovaries to try to improve egg production and pregnancy rates. The study…

This study is testing whether injecting a woman's own concentrated platelets into her ovaries can improve egg production during fertility treatments. Researchers want to see if this approach helps women who typically produce very few eggs during IVF. The trial will measure whethe…

This study tests a new way to detect early damage in the feet of people with diabetes. By measuring how the skin on the bottom of the foot responds to pressure, researchers hope to find signs of trouble before ulcers form. The study will include 200 people, both with and without …

This study tests a new wearable device that uses harmless electrical signals to monitor how well the bladder empties in men with an enlarged prostate. The device is worn on the lower belly and aims to replace inconvenient clinic-based urine flow tests. Forty participants will use…

This study is for people with chest pain but no major blockages in their heart arteries. It tests a new wireless pressure catheter that measures blood flow in tiny heart vessels to diagnose microvascular dysfunction. About 114 participants will undergo the procedure, and results …

This study tests whether a specific probiotic mixture can prevent allergic diseases in breastfed infants who received antibiotics within their first month of life. Researchers will give the probiotics or a placebo to 400 babies and track allergy development, gut bacteria changes,…

This study tests whether a 12-week program focusing on diet, exercise, sleep, and nutrition can prevent or slow early fertility decline in women aged 20-40. About 384 women with early signs of reduced ovarian reserve will be randomly assigned to either the lifestyle program or st…

This study compares two ways to give steroid medicine to people with chronic sinusitis who have lost their sense of smell due to blocked nasal passages. One group will get standard steroid spray, while the other gets steroid drops placed directly into the smell area. The goal is …

This study tests whether special foot exercises (foot core control training) can reduce pain and improve walking in people with chronic plantar fasciitis, a condition causing long-term heel pain. Researchers will measure big toe movement and walking patterns in 34 adults aged 25-…

This study tests whether a traditional Chinese medicine hand-foot soak can reduce nerve pain and skin reactions caused by chemotherapy. Researchers will enroll 300 adults with solid tumors who have developed these side effects. Participants will use the soak and report changes in…

This study tests a new digital system that uses wearable sensors and AI to guide knee rehabilitation at home. It includes 160 adults aged 18-50 with ACL tears or patellar knee pain. The goal is to see if this smart system improves knee function and reduces pain better than tradit…

This study tests whether adding single-leg 20-degree squats to standard physical therapy can improve how people walk after anterior cruciate ligament (ACL) reconstruction surgery. About 48 adults aged 18 to 45 with a recent ACL tear and weak thigh muscles will be enrolled. Resear…

This study looks at whether using a pillow placed behind the shoulder after rotator cuff repair surgery can lower pain and improve sleep. About 126 adults aged 40-70 who are having this surgery will choose whether to use the pillow. Their pain, sleep quality, and shoulder functio…

This study looks at whether losing weight can make standard psoriasis treatments more effective for overweight or obese patients with moderate-to-severe plaque psoriasis. About 70 participants will either receive standard care alone or standard care plus a personalized weight los…

This study compares two silver dressings—a soft foam type and a traditional type—for treating infected chronic wounds. About 40 adults with ulcers will be randomly assigned to one dressing to see which heals wounds faster and costs less. The goal is to find a better way to treat …

This study tests whether a personalized exercise program created by artificial intelligence can improve knee movement and reduce pain in people with rheumatoid arthritis. About 147 adults with mild to moderate arthritis will be split into three groups: one using the AI system, on…

This study looks at whether adding steroid nose drops to smell training helps people who lost their sense of smell after an infection. About 100 adults aged 18-65 with poor smell will be split into two groups: one gets nose drops plus training, the other gets training alone. The …

This study tests whether using virtual reality (VR) games before surgery can help older adults with a common brain condition (cerebral small vessel disease) keep their thinking skills sharp after the operation. Researchers will enroll 240 patients aged 60 and older who are schedu…

This study aims to create a new CT scoring system to better understand how blockages in the nose's smell center relate to loss of smell in people with central compartment atopic disease (CCAD), a type of nasal allergy. Researchers will compare this new method with traditional CT …

This study aims to create an AI-based system that helps people with diabetes avoid repeat foot ulcers. Researchers will follow 200 adults whose foot ulcers have healed, using a home monitoring tool and personalized follow-up plans to catch early warning signs. The goal is to redu…

This study aims to build an AI-powered early warning system to help people with diabetes avoid repeat foot ulcers. Researchers will follow 200 patients whose foot ulcers have healed, using smart tools to detect early signs of recurrence and guide home care. The goal is to catch p…

This study focuses on extremely preterm infants (born before 32 weeks) who have a heart condition called hsPDA, where a blood vessel fails to close after birth. Researchers will collect blood samples and health data to create a model that predicts which babies are at highest risk…

This study looks at 200 people with Charcot-Marie-Tooth disease (CMT) who have foot problems that make walking hard. It compares two treatments: foot surgery followed by rehabilitation, versus physical therapy alone. Researchers will track walking speed and endurance for up to tw…

This study will create a health management platform for people with early-stage Cardiovascular-Kidney-Metabolic (CKM) syndrome, a condition linking heart disease, kidney problems, and metabolic issues like diabetes. Researchers will enroll 150 adults aged 18-75 who can use a smar…