Peking University Third Hospital

This study tests whether a new combination of drugs (enfortumab vedotin plus toripalimab) works better than standard chemotherapy before bladder cancer surgery. About 58 adults with high-risk muscle-invasive bladder cancer will be randomly assigned to one of the two treatments fo…

This study compares two surgical methods to treat chronic ankle instability in people who also have joint hypermobility (very flexible joints). One method adds a special tape for extra support. The goal is to see which surgery provides better stability and fewer repeat injuries. …

This study looks at whether a traditional Chinese herbal prescription called Fuzheng Yangxin can help people recover more quickly after coronary artery bypass grafting. Researchers will follow 300 patients with a specific post-surgery syndrome (Qi-Yin deficiency) to see if the he…

This study tests a new treatment using natural killer (NK) cells, a type of immune cell, for adults with aggressive brain tumors that have not responded to standard therapies. The NK cells are grown in a lab and then given through a vein and directly into the brain. The main goal…

This study tests a combination of two drugs, glofitamab and lenalidomide, in people with a fast-growing type of lymphoma (mantle cell lymphoma) that has come back or not responded to treatment, especially after a BTK inhibitor stopped working. About 43 adults will receive the dru…

This trial tests whether a natural ointment called Xiang Lei Ointment can help heal diabetic ulcers better than standard care alone. The ointment aims to reduce inflammation and promote wound repair. The study will enroll 56 adults with diabetes and a foot or leg ulcer that is in…

This study tests a drug called teprotumumab N01 in 50 adults with thyroid eye disease, an autoimmune condition that causes bulging eyes and discomfort. Participants receive the drug and are monitored with special PET and MRI scans to see if inflammation and eye changes improve. T…

This study tests whether tetrandrine tablets can improve lung function in people with interstitial lung disease caused by connective tissue disease (like lupus or scleroderma). One hundred adults will receive either tetrandrine or a placebo for 24 weeks, alongside their usual tre…

This study is testing a cream called ruxolitinib on 170 people with vitiligo, a skin condition that causes white patches. The goal is to find out what factors help the cream work best. Participants must be 12 or older and have mild to moderate vitiligo. They will stop other treat…

This clinical trial compares two drugs for shingles (herpes zoster): brivudine and famciclovir. The study will enroll 140 adults with acute shingles to see which drug better reduces pain and speeds up healing. Researchers will track pain levels for up to 90 days and monitor for l…

This study tests a new antibacterial absorbable dressing on 30 adults with chronic non-healing wounds. The dressing is designed to break down in the body and help wounds heal faster. Researchers will measure how much the wound shrinks after 3 weeks and how many wounds fully close…

This study tests a combination of three drugs—pomalidomide, orelabrutinib, and zuberitamab—in people with untreated mantle cell lymphoma, a type of blood cancer. The goal is to see if the treatment can reduce cancer cells to undetectable levels after six cycles. Participants who …

This study tests a new, less invasive way to perform coronary artery bypass grafting (CABG) that avoids touching the aorta. The new method uses a small incision in the left chest, while the standard approach opens the chest fully. Researchers will compare how well the bypass graf…

This study tests a new type of ultrasound called super-resolution ultrasound (SRUS) to see if it can better tell the difference between benign (non-cancerous) and malignant (cancerous) swollen lymph nodes. About 779 adults with abnormal lymph nodes will receive an injection of ul…

This study looks at different preventive surgeries for women with gene mutations that raise their risk of ovarian cancer. Researchers want to see if removing the fallopian tubes first and delaying ovary removal works as well as standard surgery or close monitoring. About 480 wome…

This study looks at whether doing exercise rehabilitation before surgery can improve bone density, tendon healing, balance, and knee function in people with an ACL tear. Researchers will follow 60 participants aged 18 to 40 who are having their first ACL reconstruction. The goal …

This study tests whether a short cognitive-behavioral program before anterior cruciate ligament (ACL) reconstruction can reduce fear of movement and improve physical function. 44 patients aged 18-45 will be randomly assigned to either the psychological intervention or standard ca…

This study compares a wearable device-based remote rehabilitation system to traditional in-person therapy for people recovering from rotator cuff surgery. 72 adults with small to medium tears will be randomly assigned to either group. The goal is to see if the wearable approach c…

This study compares traditional in-person rehab with a new intelligent wearable system for frozen shoulder patients. 42 adults aged 40-60 will use either standard therapy, the smart system, or a combination. The goal is to see if the wearable approach improves shoulder movement a…

This study looks at whether adding visual-guided balance training to standard rehab can improve knee function and walking patterns in people who had ACL reconstruction. 45 patients will be split into two groups: one doing standard rehab plus regular balance exercises, and the oth…

This study looks at whether a special imaging technique called Quantitative Flow Reserve (QFR) can help predict how well a blood vessel graft will work after coronary artery bypass surgery. Researchers will follow 110 patients for one year after surgery to check if the grafts sta…

This study uses data from 4,700 kidney cancer patients treated at a single hospital over 12 years. The goal is to create a new model that better predicts how the disease will progress, especially for patients with a tumor thrombus. Researchers will also test whether using this mo…

This study will follow 200 adults with rheumatoid arthritis (RA) that does not respond well to standard treatments, known as refractory RA. The goal is to learn more about why some people have hard-to-treat RA and find clues to better personalize their care. Participants will be …

This study will follow about 4,500 people with cardiovascular-kidney-metabolic (CKM) syndrome for at least 3 years. Researchers will collect blood samples and use stress echocardiograms to look for biomarkers that predict major heart problems like heart attack or stroke. The goal…

This study compares the usual timing of the 'trigger' shot in IVF with a 1-2 day delay. Researchers want to see if waiting longer leads to more high-quality embryos and higher live birth rates. About 834 women undergoing their first or second IVF cycle will take part.