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New ultrasound technique could spot cancer in lymph nodes without a needle

NCT ID NCT07155954

Recruiting now Diagnosis Sponsor: Peking University Third Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new type of ultrasound called super-resolution ultrasound (SRUS) to see if it can better tell the difference between benign (non-cancerous) and malignant (cancerous) swollen lymph nodes. About 779 adults with abnormal lymph nodes will receive an injection of ultrasound contrast agent, and the movement of tiny bubbles will be tracked to create a detailed map of blood vessels. The goal is to improve diagnostic accuracy and potentially reduce the need for invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ultrasound contrast agent (Sonovue or Sonazoid)
What this could lead to
If successful, this could give doctors a more accurate, non-invasive way to tell if swollen lymph nodes are cancerous or not, reducing unnecessary biopsies.
What could go wrong
This is an early-stage diagnostic study, not a treatment. The technique may not prove more accurate than current methods, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

lymph node tuberculosis Lymphadenopathy lymphatic system disorder lymphoma metastatic malignant neoplasm in the lymph nodes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHADENOPATHY LYMPHATIC TUBERCULOSIS LYMPHNODE METASTASIS LYMPHOMA

Contacts and locations

Locations

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100049, China

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