Peking University Cancer Hospital & Institute

This study compares two different drug combinations for people with advanced kidney cancer whose first treatment has stopped working. 116 participants will be randomly assigned to receive either vorolanib tablets plus everolimus or the standard drug sunitinib. The goal is to see …

This study is testing if adding radiation and two immunotherapy drugs to standard chemotherapy works better for controlling advanced rectal cancer that has spread. It will involve 106 patients with a specific genetic type of cancer. Participants will be randomly assigned to recei…

This study is testing a two-part treatment given before surgery for stage II-III rectal cancer. First, patients receive a short, focused course of radiation designed to spare certain lymph nodes. Then, they receive an immunotherapy drug (a PD-1 inhibitor) to help the immune syste…

This study is testing whether increasing the dose of the drug firmonertinib can help patients with advanced lung cancer who have a specific genetic mutation. The trial is for people whose cancer has only stayed stable, not shrunk, after 8 weeks on the standard lower dose. Researc…

This study is testing whether adding a new immunotherapy drug called adebrelimab to standard chemotherapy and radiation can better control limited-stage small-cell lung cancer. It will enroll 30 patients to see if this combination is safe and effective at keeping the cancer from …

This study is testing whether a new drug called SHR-A1811 works better and is safer than the current standard treatment for people with advanced HER2-positive breast cancer whose cancer stopped responding to their first targeted therapy. About 100 adults with this specific type o…

This study is testing whether adding an immunotherapy drug called adebrelimab to standard chemoradiation helps control limited-stage small cell lung cancer longer. It will compare two approaches: starting immunotherapy early with chemotherapy versus adding it later as maintenance…

This study is testing whether adding a drug called pyrotinib to two standard medications (trastuzumab and pertuzumab) can better control advanced HER2-positive breast cancer after initial chemotherapy. It will follow 42 patients in a real-world setting to see if this combination …

This study is testing a drug called ivonescimab, given alone or with chemotherapy, to treat patients with non-small cell lung cancer that can be removed by surgery. The goal is to see if using less chemotherapy based on a patient's tumor marker (PD-L1) can reduce side effects whi…

This study is testing whether a high dose of the drug firmonertinib, combined with bevacizumab, can effectively shrink tumors before surgery in patients with a specific type of lung cancer (EGFR-mutated, non-small cell). The goal is to see if this pre-surgery treatment helps remo…

This study is for people with a specific type of lung cancer (limited-stage small cell) who have finished their initial chemo-radiation treatment. Researchers will use a special blood test to look for tiny traces of leftover cancer. If the test is positive, patients will receive …

This study is testing a standardized treatment plan for a serious complication called an esophageal fistula, which is a hole that can form in the esophagus of patients with advanced esophageal cancer. The plan involves sealing the hole with a stent, treating infections, providing…

This study is testing an investigational drug called SHR-A1811 for women with advanced HER2-positive breast cancer that has spread to the brain. It aims to see if the drug is safe and effective at controlling the cancer in the brain and spinal fluid. The trial will include two gr…

This study is testing a new robotic system to help surgeons find and mark small, hard-to-locate spots in the lung before a minimally invasive surgery. The robot uses a special dye to make these spots visible during the operation. Researchers want to see if this method is safe, ef…

This study is testing a new type of PET scan that detects a protein called PD-L1 in tumors. Researchers want to see if this scan can identify which patients with lung cancer, melanoma, or other solid tumors are most likely to benefit from immunotherapy drugs. The scan uses a radi…

This study is testing whether taking capsules containing a patient's own probiotics can help reduce severe bowel problems that often occur after rectal cancer surgery and the closure of a temporary ileostomy. The trial will involve 40 patients who will take the probiotic capsules…

This study is testing whether a traditional Chinese medicine hand and foot bath can help reduce nerve pain and numbness caused by a common breast cancer chemotherapy drug. Researchers will compare the herbal soak to a standard vitamin B12 supplement in 78 participants. The main g…

This study aims to understand how esophageal cancer changes over time by tracking patients through blood tests, imaging scans, and tissue samples. Researchers will follow 255 people with esophageal cancer who are either recovering from surgery or receiving immunotherapy treatment…