New scan may better spot hidden cancer in lymph nodes

NCT ID NCT07552207

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare two different PET/MRI scans to see which one is better at finding lymph node metastases in people with middle to high rectal cancer. Thirty participants will receive both types of scans before surgery. The goal is to see if the newer tracer, [68Ga]Ga-CTR-FAPI, can detect cancer spread more accurately than the standard 18F-FDG tracer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Two radioactive tracers: 18F-FDG and [68Ga]Ga-CTR-FAPI, given as injections before PET/MRI scans

What this could lead to

If successful, this could lead to more accurate detection of cancer spread in lymph nodes, helping doctors choose the best treatment for rectal cancer patients.

What could go wrong

This is a small, early-stage study with only 30 participants, so results may not apply to all patients. The new tracer may not prove significantly better than the standard one.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Lymphatic Metastasis metastatic malignant neoplasm in the lymph nodes rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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